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Artikel-Nr: (BOSSBS-4910R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4910R

Beschreibung: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4862R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4862R

Beschreibung: SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form a complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4937R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4937R

Beschreibung: Cystatin A and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. Cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10034R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10034R

Beschreibung: Anti-CSN1S2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10012R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10012R

Beschreibung: E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10029R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10029R

Beschreibung: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10014R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10014R

Beschreibung: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0968R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0968R

Beschreibung: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0995R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0995R

Beschreibung: Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is up-regulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13298R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13298R

Beschreibung: CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10419R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10419R

Beschreibung: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10427R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10427R

Beschreibung: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10648R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10648R

Beschreibung: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10722R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10722R

Beschreibung: Anti-SEB Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-7519R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7519R

Beschreibung: Anti-SEMA4A Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10726R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10726R

Beschreibung: Anti-CDK2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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