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Artikel-Nr: (BOSSBS-15155R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15155R

Beschreibung: C2orf61 (chromosome 2 open reading frame 61), also known as FLJ40172, is a 177 amino acid protein encoded by a gene that maps to human chromosome 2p21. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-15151R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15151R

Beschreibung: C2orf50 (chromosome 2 open reading frame 50), also known as FLJ25143 or MGC149401, is a 162 amino acid protein that is encoded by a gene located on human chromosome 2p25.1. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-15145R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15145R

Beschreibung: Anti-C2GNT3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-9358R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9358R

Beschreibung: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-9375R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9375R

Beschreibung: MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms.

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Artikel-Nr: (BOSSBS-9365R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9365R

Beschreibung: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0625R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0625R

Beschreibung: Anti-ZNF268 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0699R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0699R

Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0716R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0716R

Beschreibung: Activates apoptosis.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13000R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13000R

Beschreibung: This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008].

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Artikel-Nr: (BOSSBS-13003R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13003R

Beschreibung: DIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11023R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11023R

Beschreibung: Anti-DNAH7 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11028R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11028R

Beschreibung: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11035R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11035R

Beschreibung: Anti-TNFAIP8L2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11014R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11014R

Beschreibung: ILVBL is a 632 amino acid single-pass membrane protein that belongs to the TPP enzyme family. Expressed in the majority of tissues, ILVBL has the highest level of expression in heart, pancreas and placenta. ILVBL is highly homologous to several bacterial enzymes, including the B isozyme of the large catalytic subunit of E. coli acetohydroxy-acid synthase (AHAS) and the oxalyl-coA decarboxylase of O. formigenes, that utilize thiamine pyrophosphate as a cofactor. ILVBL binds one magnesium ion and one thiamine pyrophosphate per subunit, and may catalyze the initial step in branched-chain amino acid biosynthesis. The gene encoding ILVBL maps to human chromosome 19p13.12 and mouse chromosome 10 C1.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11020R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11020R

Beschreibung: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

UOM: 1 * 100 µl

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