Sie suchten nach: Bioss

Artikel-Nr: (BOSSBS-8502R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8502R

Beschreibung: Anti-CASP9 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8033R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8033R

Beschreibung: Anti-COLEC10 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-7750R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7750R

Beschreibung: Anti-KIF20A Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11687R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11687R

Beschreibung: PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-7988R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7988R

Beschreibung: Anti-CEP85 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2272R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2272R

Beschreibung: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13570R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13570R

Beschreibung: The BTB is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. ZBTB3 (zinc finger and BTB domain containing 3) is a 574 amino acid protein that contains one BTB (POZ) domain and two C2H2-type zinc fingers. Localized to the nucleus, ZBTB3 is thought to play a role in transcriptional regulation events. The gene encoding ZBTB3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2260R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2260R

Beschreibung: Anti-ELOVL1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2222R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2222R

Beschreibung: Anti-cellulase Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12345R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12345R

Beschreibung: HEM1 is a 1,127 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the cell membrane. One of several members of the highly conserved HEM family of tissue-specific transmembrane proteins, HEM1 is expressed in cells of hematopoietic origin where it is thought to play an important role in oogenesis. The gene encoding HEM1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11681R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11681R

Beschreibung: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11683R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11683R

Beschreibung: Thimet oligopeptidase, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family. The gene for the protein maps against chromosome 19q13.3. Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments. It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length. Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, lung and kidney.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11691R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11691R

Beschreibung: FLAD1 is a 587 amino acid protein where its N-terminus belongs to the moaB/mog family and its C-terminus belongs to the PAPS reductase family. Existing as five alternatively spliced isoforms, FLAD1 localizes to the cytoplasm and utilizes magnesium as a cofactor. FLAD1 is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor flavin adenine dinucleotide (FAD). It is suggested that the molybdenum cofactor biosynthesis protein-like region of FLAD1 may not be functional.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11689R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11689R

Beschreibung: This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11701R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11701R

Beschreibung: Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product huntingtin. HIP1 (huntingtin-interacting protein 1), a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels, and exhibits nearly identical subcellular fractionation as huntingtin. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8369R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8369R

Beschreibung: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson’s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.

UOM: 1 * 100 µl

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