Sie suchten nach: Biosensis

Artikel-Nr: (BSENR-093-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-093-500

Beschreibung: FUNCTION: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SUBUNIT: Homodimer, associated by noncovalent forces. SUBCELLULAR LOCATION: Secreted protein. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENR-066-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-066-500

Beschreibung: BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain.FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENM-1300-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1300-100

Beschreibung: Recognizes native and denatured forms of Cyan Fluorescent Protein (CFP) and its variants: Enhanced Green Fluorescent Protein (EGFP), Yellow Fluorescent Protein (YFP), Enhanced Yellow Fluorescent Protein (EYFP) and Cyan Fluorescent Protein (CFP).

UOM: 1 * 100 µG

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Artikel-Nr: (BSENM-1315-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1315-100

Beschreibung: Designed to detect Red Fluorescent Protein (RFP) and its variants in ELISA (sandwich or capture), immunoblotting, immunoprecipitation and immunohistochemistry.

UOM: 1 * 100 µG

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Artikel-Nr: (BSENR-1494-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1494-50

Beschreibung: Endomorphins 1 and 2 are endogenous opioid peptides which have the highest affinity for the mu-opioid receptors. Located in various parts of the brain and interacts with mu-opioid receptors and produces analgesia.

UOM: 1 * 50 µG

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Artikel-Nr: (BSENS-060-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : S-060-50

Beschreibung: FUNCTION: Seems to promotes the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 50 µG

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Lieferant: Biosensis

Beschreibung: The Neurotrophin Antibody Kit contains a collection of sheep antibodies raised against BDNF, NGF, NT3 and NT4/5. The kit is completed with one vial of normal sheep IgG for use as negative control. This kit presents a cost-effective way to investigate neurotrophin protein expression and function by immunological techniques such as immunohistochemistry, ELISA, and inhibition of biological activity.

Artikel-Nr: (BSENM-1778-50-B)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1778-50-B

Beschreibung: Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.

Biosensis' biotinylated proNGF antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. The ability of biotinylated proNGF antibody to detect proNGF has been validated by WB.

UOM: 1 * 50 µG

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Artikel-Nr: (BSENG-1784-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : G-1784-100

Beschreibung: Apolipoprotein E (ApoE) is a lipoprotein involved in fat metabolism and acts as cholesterol carrier between cells and across tissues. On a genetic level, three APOE alleles are described, APOE2, APOE3 and APOE4. These alleles give rise to six APOE isoforms, which are differentially implicated in various diseases. In the peripheral system, APOE4 is linked to increased risk of atherosclerosis. In the CNS, the ability of APOE4 in clearing beta-amyloid is impaired, while APOE3 and APOE2 are more efficient in performing this task. The APOE4 genotype in particular has been linked to increased risk for developing Alzheimer's Disease.

UOM: 1 * 100 µG

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Artikel-Nr: (BSENM-1648-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1648-100

Beschreibung: Anti-DCX Mouse T4 Antibody [clone: 30]

UOM: 1 * 100 µG

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Artikel-Nr: (BSENM-1656-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1656-100

Beschreibung: Anti-UBQL2 Mouse T4 Antibody [clone: 6H9]

UOM: 1 * 100 µG

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Artikel-Nr: (BSENM-1813-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1813-100

Beschreibung: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Ref: uniprot.org. Antibody is specific for parvalbumin and does not recognize closely related proteins calretinin and calbindin as determined by Western Blotting.

UOM: 1 * 100 µG

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Artikel-Nr: (BSENC-1798-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : C-1798-50

Beschreibung: Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org. Antibody is specific for calbindin and does not recognize closely related proteins parvalbumin and calretinin as determined by Western Blotting.

UOM: 1 * 50 µl

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Artikel-Nr: (BSENM-1384-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1384-50

Beschreibung: Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein (MBP). MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system. A detailed immunochemical examination of monoclonal and polyclonal antibody responses to MBP and its peptides has revealed the existence of as many as 27 antigenic determinants, many of them conformational. Topological mapping of the potential antigenic determinants onto a model of MBP secondary structure places these determinants within 11 separate regions of the molecule, including those portions that have been found to be encephalitogenic. The message for myelin basic protein is selectively translocated to the ends of the cell processes. Immunization with myelin-associated antigens including MBP significantly promotes recovery after spinal cord contusion injury in the rat model. FUNCTION: Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). SUBUNIT: Homodimer (By similarity). SUBCELLULAR LOCATION: Myelin membrane; peripheral membrane protein; cytoplasmic side. Cytoplasmic side of myelin. TISSUE SPECIFICITY: Found in both the central and the peripheral nervous system.

UOM: 1 * 50 µl

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Artikel-Nr: (BSENR-1684-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1684-500

Beschreibung: Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENM-1407-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1407-100

Beschreibung: This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. The enzyme also binds to free monoubiquitin and may prevent its degradation in lysosomes (ref: SWISSPROT).

UOM: 1 * 100 µl

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