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Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-1619R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4237R-A750

Anti-BMPR2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-4237R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4237R-A750
Beschreibung: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-4237R-FITC

Anti-BMPR2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-4237R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4237R-FITC
Beschreibung: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1619R-CY5.5

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1619R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-CY5.5
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl
Image Unavailable-H27329.MD

BMPS (3-Maleimidopropionic acid N-hydroxysuccinimide ester) 99%

Lieferant: Thermo Fisher Scientific
Beschreibung: BMPS (3-Maleimidopropionic acid N-hydroxysuccinimide ester) 99%

Sicherheitsdatenblätter Zertifikate

Image Unavailable-BOSSBS-1619R-HRP

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Artikel-Nr: (BOSSBS-1619R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-HRP
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11606R-CY5

Anti-TWSG1 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11606R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11606R-CY5
Beschreibung: Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1509R-HRP

Anti-BMPR1A/CD292 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Artikel-Nr: (BOSSBS-1509R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1509R-HRP
Beschreibung: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-HRP

Anti-T1 gamma Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-3582R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-HRP
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-CY7

Anti-T1 gamma Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-3582R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-CY7
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-A750

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-3582R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-A750
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-A488

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-3582R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-A488
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1778R-CY5

Anti-GATA4 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-1778R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1778R-CY5
Beschreibung: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11606R-A488

Anti-TWSG1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-11606R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11606R-A488
Beschreibung: Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-A350

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-3582R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-A350
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3582R-A680

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-3582R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3582R-A680
Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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