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Artikel-Nr: (BOSSBS-2225R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2225R
Beschreibung: Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12173R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12173R-A350
Beschreibung: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.
UOM: 1 * 100 µl


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Artikel-Nr: (BOSSBS-1288R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1288R-CY5
Beschreibung: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer; [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1288R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1288R-CY7
Beschreibung: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer; [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12948R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12948R-FITC
Beschreibung: CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome.
UOM: 1 * 100 µl


Lieferant: Merck
Beschreibung: Zur Dokumentation der Analysenwerte können wahlweise ein Standard-Rechner oder ein Drucker angeschlossen werden.
Lieferant: Brady
Beschreibung: Accessories for Brady Printer Models M511 and M211.

Artikel-Nr: (BOSSBS-11558R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11558R-HRP
Beschreibung: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11558R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11558R-CY3
Beschreibung: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
UOM: 1 * 100 µl


Artikel-Nr: (1.11151.0001)
Lieferant: Merck
Hersteller Artikel Nummer : 1.11151.0001
Beschreibung: Merck hat eine Reihe von Anwendungen ermittelt, für die eine spezielle Kombination aus Tests für den Einsatz vor Ort erforderlich ist. Die Palette der Kompaktlabors erfüllt diese Anforderungen mit einem robusten, tragbaren Koffer aus Kunststoff, der als Arbeitsfläche dient und alle für die Analyse notwendigen Kits mit Geräten und Reagenzien enthält.
UOM: 1 * 1 SET

Lieferant: LABCONCO
Beschreibung: XPert™ balance enclosures provide user protection by keeping powders, particulates and fume contained during weighing procedures. They are well suited for pharmaceutical research and other laboratory applications involving weighing of toxic substances. These vented balance safety enclosures may be ducted to the outside or connected to the FilterMate Portable Exhauster to be exhausted back into the laboratory through HEPA filters, carbon filters, or a combination of both HEPA and carbon filters.

Artikel-Nr: (BOSSBS-1794R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1794R-CY5
Beschreibung: This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11558R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11558R-A750
Beschreibung: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11558R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11558R-CY7
Beschreibung: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6909R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6909R-HRP
Beschreibung: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6909R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6909R-A488
Beschreibung: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


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