Sie suchten nach: genome

Artikel-Nr: (BOSSBS-6905R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6905R-A488

Beschreibung: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6822R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6822R

Beschreibung: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4503R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4503R-CY7

Beschreibung: The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6816R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6816R-HRP

Beschreibung: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6816R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6816R-A680

Beschreibung: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6816R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6816R

Beschreibung: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-3999R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3999R-A350

Beschreibung: Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-3999R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3999R-A488

Beschreibung: Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6394R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6394R-A647

Beschreibung: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6394R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6394R-A555

Beschreibung: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6394R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6394R-A488

Beschreibung: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-9314R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9314R-A680

Beschreibung: MAP7D1 (MAP7 Domain Containing 1) is a Protein-Coding gene. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is MAP7.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-3927R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3927R-A680

Beschreibung: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8024R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8024R-HRP

Beschreibung: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8026R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8026R-CY5.5

Beschreibung: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5827R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5827R-CY7

Beschreibung: PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

UOM: 1 * 100 µl

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