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Artikel-Nr: (BOSSBS-9315R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9315R

Beschreibung: The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6581R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6581R-A750

Beschreibung: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesises mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-3309R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3309R-A750

Beschreibung: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13338R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13338R-CY7

Beschreibung: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5663R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5663R

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (PEAK40-1220EU)

Lieferant: PEAK SCIENTIFIC

Hersteller Artikel Nummer : 40-1220EU

Beschreibung: The AD302L is a useful attachment for any laboratory's external source of air, removing moisture and ensuring the delivery of dry air. Moisture content in house air can contaminate lab instrumentation, impacting on results and in some cases damaging the instrument itself. Compact in size, wall-mountable and light, the AD302L requires little space and its few moving parts mean minimal maintenance is required.

UOM: 1 * 1 ST

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Artikel-Nr: (PEAK40-1142EU)

Lieferant: PEAK SCIENTIFIC

Hersteller Artikel Nummer : 40-1142EU

Beschreibung: The AD140L is a useful attachment for any laboratory's external source of air, removing moisture and ensuring the delivery of dry air. Moisture content in house air can contaminate lab instrumentation, impacting on results and in some cases damaging the instrument itself. Compact in size, wall-mountable and light, the AD140L requires little space and its few moving parts mean minimal maintenance is required.

UOM: 1 * 1 ST

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Artikel-Nr: (BOHLD785-24)

Lieferant: Bohlender

Hersteller Artikel Nummer : D785-24

Beschreibung: This blue screw cap is made of PP with GLS threads. with movable reduction body made of PTFE for transition to GL threads. The body can be moved independently from the screw cap so that the completely assembled reduction can be removed and fixed on another vessel without the risk of disarranging the tubing or cable. The product is only exposed to PTFE.

UOM: 1 * 1 ST

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Artikel-Nr: (BOSSBS-11804R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11804R-A488

Beschreibung: Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects golgi structure, and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12866R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12866R-A647

Beschreibung: Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects Golgi structure and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the Golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5660R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5660R-CY5.5

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5660R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5660R-CY5

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5661R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5661R-A680

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5661R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5661R-CY5.5

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-5661R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5661R-CY5

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5660R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5660R-FITC

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

Sale