Sie suchten nach: L(+)-Asparagins\u00E4ure

Artikel-Nr: (BOSSBS-12937R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12937R-A647

Beschreibung: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

UOM: 1 * 100 µl

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Lieferant: Thermo Fisher Scientific

Beschreibung: D-Asparagine monohydrate

New Product

Artikel-Nr: (BOSSBS-6800R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6800R-CY3

Beschreibung: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

UOM: 1 * 100 µl

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Lieferant: Thermo Fisher Scientific

Beschreibung: (±)-Asparaginsäure 98

Sicherheitsdatenblätter Zertifikate

Artikel-Nr: (BOSSBS-6800R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6800R-CY5.5

Beschreibung: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

UOM: 1 * 100 µl

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Lieferant: Apollo Scientific

Beschreibung: L(+)-Asparaginsäure

Zertifikate

Lieferant: Apollo Scientific

Beschreibung: Chiral intermediate for pharmaceuticals and agrochemicals; Materials for peptides.

Artikel-Nr: (BOSSBS-13322R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13322R-FITC

Beschreibung: Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER). Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway. It specifically removes the distal alpha 1,2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor. Glucosidase I contains a short cytosolic tail, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER. Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), which is characterized by generalized hypotonia, dysmorphic features, hepatomegaly, hypoventilation, feeding problems, seizures and death. Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, namely Arg486Thr and Phe652Leu, that affect polypeptide folding and active site formation.

UOM: 1 * 100 µl

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Artikel-Nr: (MOLE15650008-100G)

Lieferant: Molekula

Hersteller Artikel Nummer : 15650008-100G

Beschreibung: L(+)-Asparagin

UOM: 1 * 100 g

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Artikel-Nr: (BOSSBS-6800R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6800R-FITC

Beschreibung: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6800R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6800R-A555

Beschreibung: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6800R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6800R-HRP

Beschreibung: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6073R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6073R-HRP

Beschreibung: Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12937R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12937R-CY7

Beschreibung: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-0473R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0473R-CY5

Beschreibung: Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12937R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12937R-CY5

Beschreibung: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

UOM: 1 * 100 µl

Sale