Sie suchten nach: Formamid

Artikel-Nr: (EHERGS09000063DM)

Lieferant: EHRENSTORFER

Hersteller Artikel Nummer : GS09000063DM

Beschreibung: [EN]VOC MIX 10000UG/ML 5X1ML 1 * 5 mL

UOM: 1 * 5 mL

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Artikel-Nr: (ENZOBMLEI3270025)

Lieferant: ENZO LIFE SCIENCES

Hersteller Artikel Nummer : BMLEI3270025

Beschreibung: URB-597 is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), which is involved in the hydrolysis of endogenous cannabinoids such as anandamide. Inhibition of FAAH may serve to enhance the analgesic effects of endogenous cannabinoids. URB-597 has been shown to inhibit FAAH in rat cortical neuron membranes and in intact neurons with IC50 values of 4.6nM and 0.5nM, respectively. The compound has also been shown to have anxiolytic effects in rats (ID50=0.15mg/kg). Because URB-597 acts on FAAH and does not interfere with the binding of anandamide to the CB1 and CB2 receptors, it is a novel tool for drug development.

UOM: 1 * 25 mg

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Artikel-Nr: (AMBDA124269-25G)

Lieferant: AMBEED

Hersteller Artikel Nummer : A124269-25G

Beschreibung: N,N'-(HEXANE-1,6-DIYL)BIS(N-(2,2,6,6-TET 1 * 25 g

UOM: 1 * 25 g

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

Artikel-Nr: (EHERGS09000064DM)

Lieferant: EHRENSTORFER

Hersteller Artikel Nummer : GS09000064DM

Beschreibung: KETONES MIXTURE 64 10000 µG/ML IN DIMETH 1 * 1 KIT

UOM: 1 * 1 KIT

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Artikel-Nr: (ENZOALX400045M100)

Lieferant: ENZO LIFE SCIENCES

Hersteller Artikel Nummer : ALX400045M100

Beschreibung: Cell permeable modulator of Ins(1,4,5)-P3-induced Ca²⁺ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca²⁺ entry (75µM).

UOM: 1 * 100 mg

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Artikel-Nr: (EHERGS09000170DM)

Lieferant: EHRENSTORFER

Hersteller Artikel Nummer : GS09000170DM

Beschreibung: USP CLASS 3 MIXTURE 170 1000 µG/ML IN DI 1 * 1 KIT

UOM: 1 * 1 KIT

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Artikel-Nr: (ENZOBMLEI3720001)

Lieferant: ENZO LIFE SCIENCES

Hersteller Artikel Nummer : BMLEI3720001

Beschreibung: A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.

UOM: 1 * 1 mg

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Lieferant: MP Biomedicals

Beschreibung: Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells.

Lieferant: SIGMA ALDRICH MICROSCOPY

Beschreibung: Acriflavine also interacts with HIF-1α (hypoxia-inducible factor 1 α) and HIF-2α, and thereby suppresses dimer formation of HIF-1 and transcriptional function. It also has negative effect on tumor growth and vascularization. Acriflavine also exhibits trypanocidal, antibacterial and antiviral activities.

Lieferant: MP Biomedicals

Beschreibung: Dextran is a high molecular weight polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(1-->6) linkages. The remaining a(1-->3) linkages account for the branching of dextran. Dextran has long and hydrophilic spacer arms that improves the performance of immobilized proteins acting on macromolecules.

Lieferant: Greiner Bio-One

Beschreibung: PS, without lid. Streptavidin coated solid phases serve as reliable binding surfaces for all types of biotinylated molecules. Numerous ligands can be biotinylated simply and reliably, and due to the low molecular weight of biotin (244 Da), the functionality of the molecules is normally not impaired. Thus streptavidin-coated solid phases make it possible to simply and rapidly isolate, determine and quantify components from a reaction mixture. By immobilising the biotinylated substance, it is also possible to reproduce complete reaction chains on a streptavidin solid phase, for example, enzyme immunoassays, enzyme activity assays, DNA hybridisation techniques, quantification of PCR products, and receptor/ligand studies.

Lieferant: Cytiva (Formerly Pall Lab)

Beschreibung: Die Biodyne® Transfermembran bietet eine hohe Sensitivität und einen minimalen Hintergrund für eine verbesserte Detektion und Auflösung. Sie sind ideal zur Nukleinsäurebestimmung.

Lieferant: MP Biomedicals

Beschreibung: Dextran is a high molecular weight polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(1-->6) linkages. Dextrans with molecular weights greater than 10,000 behave as if they are highly branched. As the molecular weight increases, dextran molecules attain greater symmetry.

Lieferant: ENZO LIFE SCIENCES

Beschreibung: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.