[-]-Deguelin ≥95% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
COX-2 inhibitor
Inhibitor of Akt (protein kinase B; PKB) in an in vitro lung carcinogenesis progression model. Inhibits cell proliferation - cells accumulate in the G2-M phase of the cell cycle. Premalignant and malignant human brochial epithelial cells are highly sensitive to deguelin compared to normal cells. Induces apoptosis. Exhibits a marked inhibitory effect on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. Inhibits cyclooxygenase-2 (COX-2) expression.
Formel:
C₂₃H₂₂O₆ Lager Temperatur: Kühlschrank |
MDL Number:
MFCD01740600 CAS-Nummer: 522-17-8 |
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