Lavendustin A ≥98%

Lieferant: ENZO LIFE SCIENCES

BMLEI1850001 BMLEI1850005
ENZOBMLEI1850001EA 194 CHF
ENZOBMLEI1850001 ENZOBMLEI1850005
Lavendustin A ≥98%
Lavendustin A

EGFR inhibitor


Cell permeable tyrosine kinase inhibitor with little effect on cAMP-dependent protein kinase (PKA) or protein kinase C (PKC). Potent and selective inhibitor of the EGF receptor tyrosine kinase (IC50=11nM). Binds to a site on the kinase which is distinct from the ATP and peptide substrate binding sites. Inhibits EGF-induced proliferation of cultured human myometrial smooth muscle cells and suppresses VEGF-induced angiogenesis in rats. Effective at 10µM in cultured leech neurons. Also inhibits NMDA-stimulated cGMP production.

Formel: C₂₁H₁₉NO₆
MW: 381.384 g/mol
MDL Number: MFCD00153822
CAS-Nummer: 125697-92-9
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