Anti-PDGFRB Rabbit Polyclonal Antibody

Lieferant: AbFrontier
LF-PA0041
ABFRLF-PA0041EA 311 CHF
ABFRLF-PA0041
Anti-PDGFRB Rabbit Polyclonal Antibody
Antikörper
Platelet-derived growth factors (PDGFs) have been implicated in the control of cell proliferation, survival and migration. The PDGF family of growth factors consists of five different disulphide-linked dimers built up of four different polypeptide chains encoded by four different genes. Theses isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors α and β. Thus far, gene-targeting experiments have been attempted to create knockout mice deficient for PDGFR-α or PDGFR-β. Those mice, however, died either at the embryonic stage or severalMore Product Information
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