Anti-PLCG Mouse Monoclonal Antibody [clone: 1F1]

Lieferant: AbFrontier
LF-MA0049
ABFRLF-MA0049EA 311 CHF
ABFRLF-MA0049
Anti-PLCG Mouse Monoclonal Antibody [clone: 1F1]
Antikörper
The mammalian Phospholipase C(PLC) family has two closely related proteins, PLC1 and PLC2. The PLC isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLC. Activated PLC catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).

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