Sie suchten nach: ProSci Inc.

Artikel-Nr: (PRSI31-022)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 31-022

Beschreibung: The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSI31-015)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 31-015

Beschreibung: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSI51-035)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 51-035

Beschreibung: During vertebrate embryogenesis, a left-right axis is established. Secreted growth factors of the TGF-beta family, including gene products derived from nodal, lefty-1 and lefty-2, play crucial roles in establishing left-right asymmetries. TGF-beta (Transforming growth factor-beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF-beta actions are directed by ligand-induced activation of TGF-beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF-beta superfamily, inhibits TGF-beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF-beta receptor. Lefty also inhibits events downstream from R-Smad phosphorylation. Lefty provides a repressed state of TGF-beta-responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF-beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (42 kDa) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28 kDa form induces MAPK activity.

UOM: 1 * 50 µG

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Artikel-Nr: (PRSIXP-5233)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5233

Beschreibung: Macrophage Inflammatory Protein 1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5223)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5223

Beschreibung: Anti-CCL7 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5228)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5228

Beschreibung: Anti-Csf1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5228BT)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5228BT

Beschreibung: Anti-Csf1 Goat Polyclonal Antibody (Biotin)

UOM: 1 * 50 µG

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Artikel-Nr: (PRSIXP-5290)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5290

Beschreibung: TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5707-M)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5707-M

Beschreibung: Anti-IL11 Mouse Monoclonal Antibody [clone: 27B1047.1]

UOM: 1 * 500 µG

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Artikel-Nr: (PRSIXP-5710-M)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5710-M

Beschreibung: Anti-NTF4 Mouse Monoclonal Antibody [clone: PEPY051_hNT-4]

UOM: 1 * 500 µG

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Artikel-Nr: (PRSIXP-5292)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5292

Beschreibung: Anti-VEGFA Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5706-M)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5706-M

Beschreibung: IL-8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 attracts neutrophils, basophils, and T-cells, but not monocytes.

UOM: 1 * 500 µG

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Artikel-Nr: (PRSIXP-5284)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5284

Beschreibung: Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5286BT)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5286BT

Beschreibung: Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.

UOM: 1 * 50 µG

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Artikel-Nr: (PRSI46-870)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 46-870

Beschreibung: Anti-MSH5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (PRSIXP-5264BT)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : XP-5264BT

Beschreibung: Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cell to cell adhesion and acts synergistically with other cytokines, probably interleukins. A soluble form is produced by proteolytic processing of isoform 1 in the extracellular domain.

UOM: 1 * 50 µG

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