Sie suchten nach: Biosensis

Lieferant: Biosensis

Beschreibung: The Biosensis proBDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, cell lysates, serum, citrate-plasma and tissue extracts only if used as directed.

Artikel-Nr: (BSENS-1234-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : S-1234-100

Beschreibung: Catenin beta is an adherens junction protein and has a role in the regulation of cell adhesion and in signal transduction through the Wnt pathway. At least 2 isoforms are produced by alternative splicing.

UOM: 1 * 100 µG

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Artikel-Nr: (BSENS-054-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : S-054-500

Beschreibung: NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENS-045-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : S-045-50

Beschreibung: FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB. SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. SIMILARITY: Belongs to the bZIP family. Fos subfamily. SIMILARITY: Contains 1 bZIP domain

UOM: 1 * 50 µG

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Artikel-Nr: (BSENR-1497-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1497-50

Beschreibung: Human Gastrin is a 101 amino acid hormone produced by G cells of the duodenum, stomach and pancreas. It stimulates secretion of hydrochloric acid by parietal cells of the stomach. Gastrin is also secreted into bloodstream.

UOM: 1 * 50 µG

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Artikel-Nr: (BSENR-1681-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1681-500

Beschreibung: Autosomal dominant mutations in presenilin 2 are the second major cause of early-onset familial Alzheimer's disease. Presenilin 2 is a multi-transmembrane protein which undergoes endoprotelysis to form an N-terminal fragment of about 29 kDa and C-terminal fragment of about 22 kDa. Presenilin 2 forms the catalytic core of the gamma-secretase complex which cleaves type 1 transmembrane proteins including the amyloid precursor protein to generate the C-terminus of the amyloid beta peptide.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENR-1686-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1686-500

Beschreibung: Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENR-1682-500)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1682-500

Beschreibung: Autosomal recessive mutations in DJ-1 cause early-onset familial Parkinson's disease. DJ-1 is considered a redox-sensitive cytoplasmic protein found in brain as well as other cell types.

UOM: 1 * 500 µG

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Artikel-Nr: (BSENR-1549-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1549-100

Beschreibung: Histone H3 is a core component of nucleosome.

UOM: 1 * 100 µl

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Artikel-Nr: (BSENR-1651-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1651-100

Beschreibung: GAP43 is very abundant protein which is found concentrated in neurons. One group discovered it as one of three proteins which becomes unregulated during the regeneration of the toad optic nerve (1). Three GAPs (Growth associated proteins) were discovered, and the number 43 comes from the apparent SDS-PAGE molecular weight of the one named GAP43. The HGNC name for this protein is, not surprisingly, GAP43. Later work showed that GAP43 does not run on SDS-PAGE in a fashion which accurately reflects its molecular weight, and that GAP43 proteins from different species may run at different apparent molecular weights. Partly due to these features GAP43 were independently discovered by several different groups and therefore has several alternate names, such as protein F1, pp46, neuromodulin, neural phosphoprotein B-50 and calmodulin-binding protein P-57. In each case the number reflects the apparent SDS-PAGE molecular weight, and underlines the unusual properties of this molecule. Mammalian GAP43 proteins contains only 226-243 amino acids, and so the real molecular weight is 23.61-25.14 kDa. GAP43 has been extensively studied and is known to be a major protein kinase C substrate and to bind calmodulin avidly. GAP43 is anchored to the plasma membrane by palmitoylation modifications.

UOM: 1 * 100 µG

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Artikel-Nr: (BSENR-1381-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1381-100

Beschreibung: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. MMP2 isoform 2 mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways. Catalytic activity of MMP2 causes cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln. (Ref: uniprot.org).

UOM: 1 * 100 µG

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Artikel-Nr: (BSENTR-150-FJB)

Lieferant: Biosensis

Hersteller Artikel Nummer : TR-150-FJB

Beschreibung: The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration. The fluorescent dye Fluoro-Jade® B (FJB), like its more purified brother Fluoro-Jade® C (FJC), is an anionic fluorescein derivative useful for the histological staining of neurons undergoing degeneration.

UOM: 1 * 30 mg

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Artikel-Nr: (BSENM-027-50-AT)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-027-50-AT

Beschreibung: Anti-TNR16 Mouse Monoclonal Antibody [clone: Clone: Me20.4] (Atto 488)

UOM: 1 * 50 µG

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Artikel-Nr: (BSENBEK-2240-2P)

Lieferant: Biosensis

Hersteller Artikel Nummer : BEK-2240-2P

Beschreibung: The Biosensis Mature BDNF/proBDNF Combo RapidTM enzyme-linked immunosorbent assay (ELISA) Kit combines individual, but complementary ELISA kits for the two most important BDNF isoforms: Mature BDNF (BSENBEK-2211) and full-length proBDNF (BSENBEK-2217).

UOM: 1 * 192 Tests

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Artikel-Nr: (BSENM-1802-50)

Lieferant: Biosensis

Hersteller Artikel Nummer : M-1802-50

Beschreibung: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Ref: uniprot.org

UOM: 1 * 50 µG

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Artikel-Nr: (BSENR-1794-100)

Lieferant: Biosensis

Hersteller Artikel Nummer : R-1794-100

Beschreibung: Beta-casein has an important role in determination of the surface properties of the casein micelles. it is cleaved into 3 chains (casoparan, casohypotensin and antioxidant peptide). Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide and induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity.

UOM: 1 * 100 µl

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