Sie suchten nach: Boster Bio

Artikel-Nr: (BSBTPB9996)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9996

Beschreibung: CIITA is a human gene which is mapped to 16p13. This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. Also, the protein binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. Several transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB10014)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB10014

Beschreibung: Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a peptide that in humans is encoded by the PYY gene. This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9999)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9999

Beschreibung: C-X-C motif chemokine 13 (CXCL13), also known as B cell-attracting chemokine 1 (BCA-1), is a protein that in humans is encoded by the CXCL13 gene. CXCL13 is a small cytokine belonging to the CXC chemokine family. Its gene is mapped to human chromosome 4 in a cluster of other CXC chemokines. This protein has contained 109 amino acids. It is expressed highly in the liver, spleen, lymph nodes and gut of humans. The protein induces chemotaxis of BLR1-expressing B cells.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9980)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9980

Beschreibung: The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9982)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9982

Beschreibung: Fatty aldehyde dehydrogenase (or Long-chain-aldehyde dehydrogenase) is an aldehyde dehydrogenase enzyme that in human is encoded in the ALDH3A2 gene on chromosome 17. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes into fatty acids. It is known to act on a variety of both saturated and unsaturated aliphatic aldehydes between 6 to 24 carbons in length, as well as dihydrophytal, a 20-carbon branched chain aldehyde. It requires NAD+ as a co-factor. The encoded enzyme is responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. ALD3H2 is expressed in the human liver and has been found to localize the microsome fraction inside the cell.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB10012)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB10012

Beschreibung: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB10006)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB10006

Beschreibung: Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB10017)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB10017

Beschreibung: Vesicle-associated membrane protein 7 (VAMP-7), also known as SYBL1, is a protein that in humans is encoded by the VAMP7 gene. This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide- sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9931)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9931

Beschreibung: Rabbit IgG polyclonal antibody for CD27 antigen(CD27) detection. Tested with WB, IHC-P in Human.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9918)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9918

Beschreibung: Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Human.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9913)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9913

Beschreibung: Rabbit IgG polyclonal antibody for Abelson tyrosine-protein kinase 2(ABL2) detection. Tested with WB, IHC-P in Human;Mouse.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9922)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9922

Beschreibung: Rabbit IgG polyclonal antibody for Caldesmon(CALD1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9955)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9955

Beschreibung: Rabbit IgG polyclonal antibody for Mucin-3A/Mucin-3B(MUC3A/MUC3B) detection. Tested with WB in Human.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9967)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9967

Beschreibung: Rabbit IgG polyclonal antibody for Transcriptional coactivator YAP1(YAP1) detection. Tested with WB in Human;Mouse;Rat.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9943)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9943

Beschreibung: Rabbit IgG polyclonal antibody for Fatty acid-binding protein, intestinal(FABP2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

UOM: 1 * 100 µG

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Artikel-Nr: (BSBTPB9954)

Lieferant: Boster Bio

Hersteller Artikel Nummer : PB9954

Beschreibung: Rabbit IgG polyclonal antibody for Matrix Gla protein(MGP) detection. Tested with WB, IHC-P in Human.

UOM: 1 * 100 µG

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