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Image Unavailable-BOSSBS-13186R-CY5

Anti-FMO3 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-13186R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13186R-CY5
Beschreibung: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11621R-CY5

Anti-GUCA2A Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11621R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11621R-CY5
Beschreibung: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Image Unavailable-BNUM1037-50

Anti-CD44 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: DF1485]

Artikel-Nr: (BNUM1037-50)
Lieferant: Biotium
Hersteller Artikel Nummer : BNUM1037-50
Beschreibung: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
UOM: 1 * 50 µl
Image Unavailable-BNC940918-500

Anti-CD44 Mouse Monoclonal Antibody (CF594) [clone: HCAM/918]

Lieferant: Biotium
Beschreibung: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Image Unavailable-BOSSBS-8059R-A555

Anti-CEMIP Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-8059R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8059R-A555
Beschreibung: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1551R-A555

Anti-PG-C/Pepsinogen 2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-1551R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1551R-A555
Beschreibung: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesised as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13186R-A680

Anti-FMO3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-13186R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13186R-A680
Beschreibung: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.
UOM: 1 * 100 µl
Image Unavailable-BNC400918-500

Anti-CD44 Mouse Monoclonal Antibody (CF640R) [clone: HCAM/918]

Lieferant: Biotium
Beschreibung: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Image Unavailable-BNUM0918-50

Anti-CD44 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: HCAM/918]

Artikel-Nr: (BNUM0918-50)
Lieferant: Biotium
Hersteller Artikel Nummer : BNUM0918-50
Beschreibung: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
UOM: 1 * 50 µl
Image Unavailable-BOSSBS-11183R

Anti-TMPRSS5 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-11183R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11183R
Beschreibung: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1551R-CY5

Anti-PG-C/Pepsinogen 2 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-1551R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1551R-CY5
Beschreibung: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesised as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13186R-A647

Anti-FMO3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-13186R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13186R-A647
Beschreibung: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13186R-A350

Anti-FMO3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-13186R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13186R-A350
Beschreibung: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1672R-A750

Anti-Duck plague Virus Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-1672R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1672R-A750
Beschreibung: Duck plague (DP) is an acute contagious disease that is highly lethal in all ages of birds from the order Anseriforms (ducks, geese, and swans). The characterisation of duck plague is tissue hemorrhage, digestive mucosal eruptions lesions of lymphoid organs and degenerative changes in parenchymatous organs. Duck plague was difficult to monitor and control, because duck plague virus established an asymptomatic carrier state in both domestic and wild waterfowls that was detectable only during the intermittent shedding period of the virus. Duck plague has resulted in significant economic losses in commercial duck industry due to high mortality rate and decreased duck egg production.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13037R-A350

Anti-DYM Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-13037R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13037R-A350
Beschreibung: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13037R-A750

Anti-Dymeclin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-13037R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13037R-A750
Beschreibung: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.
UOM: 1 * 100 µl
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