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Artikel-Nr: (BOSSBS-10381R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10381R-FITC
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3418R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3418R-HRP
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl


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Lieferant: VWR Collection
Beschreibung: Die mobilen Colorimeter sind für präzise Wasseranalysen konzipiert.

Artikel-Nr: (BOSSBS-3860R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-A647
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3860R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-CY7
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Artikel-Nr: (MFLX07571-02)
Lieferant: Avantor Fluid Handling
Beschreibung: Probentiefe bis auf 7.9 Meter (26 Fuß) herab.
UOM: 1 * 1 ST

UL Listed ISO9001 CE Compliant CSA Certified 2 year warranty


Artikel-Nr: (BOSSBS-1619R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-A488
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1619R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-CY3
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1619R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-A680
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0699R-CY5.5
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0699R-CY7
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3818R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3818R-CY5.5
Beschreibung: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3818R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3818R-FITC
Beschreibung: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
UOM: 1 * 100 µl


Artikel-Nr: (732-3335)
Lieferant: VWR Collection
Beschreibung: Compact and portable, the cap mat applicator is very easy to use, requiring only one operation of the system to produce an accurate and tight seal on a wide range of both collection and shallow well microplates.
UOM: 1 * 1 ST


Lieferant: VWR Collection
Beschreibung: Leitfähigkeitsmessgerät, VWR®

Artikel-Nr: (BOSSBS-1619R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1619R-CY5
Beschreibung: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
UOM: 1 * 100 µl


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