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Artikel-Nr: (BOSSBS-12933R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12933R-A680
Beschreibung: Chymotrypsins are digestive enzymes that can perform proteolysis by cleaving peptides at the carboxyl side of tyrosine, tryptophan, leucine and phenylalanine, although over time they can also hydrolyse other amide bonds, especially those with leucine-donated carboxyls. Chymotrypsins cleave peptide bonds by attacking the non-reactive carbonyl group with a powerful nucleophile, which momentarily becomes covalently bonded to the substrate to form an intermediate. Chymotrypsin B (CTRB1) and Chymotrypsin B2 (CTRB2) are synthesised in the pancreas by protein biosynthesis as precursors that are enzymatically inactive, but become active as three polypeptide molecules that are interconnected by disulfide bonds.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11069R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11069R
Beschreibung: Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.
UOM: 1 * 100 µl


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Artikel-Nr: (BOSSBS-11069R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11069R-HRP
Beschreibung: Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.
UOM: 1 * 100 µl


Artikel-Nr: (786-320)
Lieferant: G-Biosciences
Hersteller Artikel Nummer : 786-320
Beschreibung: The Fluoro™ Protease Assay Kit is designed for the quantitative determination of proteases present in a protein sample. The assay uses fluorescein isothiocyanate (FITC)-labelled casein as a general protease substrate. The fluorescein label on the FITC-casein is highly quenched. When the proteases present in the sample of interest digest the FITC-casein substrate into smaller peptides, the quenching of the fluorescence label is relieved and the fluorescence of the substrate is increased. The fluorescence of the FITC-labeled peptide is measured with excitation at 485 nm and emission at 530 nm to determine protease activity. The kit detects picogram level of proteases present in the sample.
UOM: 1 * 1 KIT


Artikel-Nr: (BOSSBS-4030R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4030R-A680
Beschreibung: Pancreatic amylase is a digestive enzyme secreted by the pancreas. It consists of a single polypeptide chain with a molecular weight of 54 kDa.Pancreatic amylase and salivary amylase are the products of separate genes and, although they share 98% amino acid sequence homology, they differ in molecular size, isoelectric point and antigenic properties. Measurement of amylase concentrations in serum is a diagnostic test for various pancreatic disorders (especially acute and relapsing pancreatitis).
UOM: 1 * 100 µl


Lieferant: Biotium
Beschreibung: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Artikel-Nr: (BOSSBS-1672R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1672R-A680
Beschreibung: Duck plague (DP) is an acute contagious disease that is highly lethal in all ages of birds from the order Anseriforms (ducks, geese, and swans). The characterisation of duck plague is tissue hemorrhage, digestive mucosal eruptions lesions of lymphoid organs and degenerative changes in parenchymatous organs. Duck plague was difficult to monitor and control, because duck plague virus established an asymptomatic carrier state in both domestic and wild waterfowls that was detectable only during the intermittent shedding period of the virus. Duck plague has resulted in significant economic losses in commercial duck industry due to high mortality rate and decreased duck egg production.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1551R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1551R-FITC
Beschreibung: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesised as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1551R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1551R-A350
Beschreibung: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesised as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-13037R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13037R-A488
Beschreibung: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1672R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1672R-A350
Beschreibung: Duck plague (DP) is an acute contagious disease that is highly lethal in all ages of birds from the order Anseriforms (ducks, geese, and swans). The characterization of duck plague is tissue hemorrhage, digestive mucosal eruptions lesions of lymphoid organs and degenerative changes in parenchymatous organs. Duck plague was difficult to monitor and control, because duck plague virus established an asymptomatic carrier state in both domestic and wild waterfowls that was detectable only during the intermittent shedding period of the virus. Duck plague has resulted in significant economic losses in commercial duck industry due to high mortality rate and decreased duck egg production.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11183R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11183R-CY3
Beschreibung: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11183R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11183R-CY7
Beschreibung: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8059R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8059R-CY5.5
Beschreibung: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
UOM: 1 * 100 µl


Artikel-Nr: (ROCKMB-114-0001)
Lieferant: Rockland Immunochemicals
Hersteller Artikel Nummer : MB-114-0001
Beschreibung: Protease <i>S.aureus</i> V8 (endoproteinase-glu-C) specifically cleaves peptide bonds on the COOH-terminal side of either aspartic or glutamic acids. In the presence of ammonium, the enzyme specificity is limited to glutamic sites. It has a molecular weight of 27000 daltons and optimum pH's of 4,0 and 7,8 with hemoglobin as the substrate. Enzyme activity is determined by the casein digestion assay.
UOM: 1 * 1 mg


Artikel-Nr: (BOSSBS-4982R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4982R-CY5
Beschreibung: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. HIV1 Gag p17, the HIV1 matrix protein is produced by the digestion of its precursor Gag p55 by HIV1 protease.
UOM: 1 * 100 µl


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