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Artikel-Nr: (BOSSBS-13046R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13046R
Beschreibung: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs Transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate Transporter that is expressed predominantly in the cerebellum. The Transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar Transport activities. EAAT5 is a glutamate Transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Artikel-Nr: (LIOF610182)
Lieferant: LIOFILCHEM
Hersteller Artikel Nummer : 610182
Beschreibung: Trockennährmedien in Pulverform, erhältlich in den Formaten 100 g, 500 g und 5 kg.
UOM: 1 * 500 g

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Artikel-Nr: (BOSSBS-13046R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13046R-CY7
Beschreibung: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs Transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate Transporter that is expressed predominantly in the cerebellum. The Transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar Transport activities. EAAT5 is a glutamate Transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-13046R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13046R-FITC
Beschreibung: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs Transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate Transporter that is expressed predominantly in the cerebellum. The Transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar Transport activities. EAAT5 is a glutamate Transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11180R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11180R
Beschreibung: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
UOM: 1 * 100 µl


Lieferant: Abcam
Beschreibung: Rabbit monoclonal [EPR23527-534] to Noradrenaline transporter - BSA and Azide free.

Lieferant: VWR Collection
Beschreibung: <p><span style="color:black">The VWR® hydrometer rack accommodates up to 10 hydrometers with diameters up to 31 mm, ensuring safe storage, efficient drying and secure transport.</span></p>

New Product

Artikel-Nr: (BOSSBS-11180R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11180R-CY3
Beschreibung: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0401R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0401R-A750
Beschreibung: No data available.
UOM: 1 * 100 µl


Lieferant: ENZO LIFE SCIENCES
Beschreibung: Inhibitor of dopamine and norepinephrine transporters

Artikel-Nr: (ENZOADICSA620E)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ADICSA620E
Beschreibung: TAP1 and TAP2 are two structurally related subunits of the Transporter associated with antigen processing (TAP). The TAP complex is a member of the ATP binding cassette (ABC) family of transmembrane Transporters. The TAP Transporter is an essential component of the MHC class I antigen presentation pathway by binding peptides in its cytosolic part and subsequently translocating the peptides into the lumen of the endoplasmic reticulum where assembly of MHC class I and pepide takes place.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-13260R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13260R-A750
Beschreibung: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3577R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3577R-A350
Beschreibung: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11907R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11907R-CY3
Beschreibung: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC genes comprise several subfamilies (ABC1, ABCA, ABCE, ABCF, MDR/TAP, MRP, ALD, OABP, GCN20 and White (also known as ABCG)). In bacteria, ABC transporters are used to import compunds that cannot be obtained by diffusion. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process or outside the cell for transport to other organs, or for secretion from the body. ABCB9 (also designated transporter associated with antigen processing (TAP)-like or TAPL) forms a homodimer, which is localized in lysosomes. It functions as an ATP-dependent peptide transporter that shows a broad peptide specificity ranging from 6-mer up to 59-mer peptides. ABCB9 transports these peptides with low affinity but high efficiency.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3577R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3577R-A647
Beschreibung: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-2540R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2540R-A680
Beschreibung: GLUT12 belongs to a family of transporters that catalyse the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.
UOM: 1 * 100 µl


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