Sie suchten nach: splicing

Artikel-Nr: (USBIS5554-58-100)

Lieferant: US Biological

Hersteller Artikel Nummer : S5554-58-100

Beschreibung: Anti-Splicing Factor, Arginine/Serine-Rich 5 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (USBIN2904-20B)

Lieferant: US Biological

Hersteller Artikel Nummer : N2904-20B

Beschreibung: Anti-NMDA 1 Receptor, N1 Splice Variant Rabbit Polyclonal Antibody

UOM: 1 * 25 µG

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Artikel-Nr: (USBIN2904A)

Lieferant: US Biological

Hersteller Artikel Nummer : N2904A

Beschreibung: Anti-NMDA 1 Receptor, C1 Splice Variant Rabbit Polyclonal Antibody

UOM: 1 * 25 µG

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Artikel-Nr: (USBIS5554-60-100)

Lieferant: US Biological

Hersteller Artikel Nummer : S5554-60-100

Beschreibung: Anti-Splicing Factor, Arginine/Serine-Rich 6 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (USBIS5554-54-100)

Lieferant: US Biological

Hersteller Artikel Nummer : S5554-54-100

Beschreibung: Anti-Splicing Factor, Arginine/Serine-Rich 3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (USBIS5554-78-100)

Lieferant: US Biological

Hersteller Artikel Nummer : S5554-78-100

Beschreibung: Anti-Splicing Factor, Arginine/Serine-Rich 14 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel-Nr: (BOSSBS-12299R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12299R-FITC

Beschreibung: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6513R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6513R-CY3

Beschreibung: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.Predominantly expressed in muscle and brain.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13229R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13229R-CY5

Beschreibung: FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2∫ and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13229R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13229R-CY3

Beschreibung: FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2∫ and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6513R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6513R-A488

Beschreibung: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.Predominantly expressed in muscle and brain.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6513R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6513R-A647

Beschreibung: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.Predominantly expressed in muscle and brain.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-9735R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9735R-HRP

Beschreibung: The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5’ and 3’ splice sites, thereby releasing introns and free tRNA molecules with 2',3' cyclic phosphates and 5'-OH termini. In addition to its role in pre-tRNA splicing, the heterotetrameric endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. TSEN2 (tRNA-splicing endonuclease subunit Sen2), also known as tRNA-intron endonuclease Sen2, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex. There are three isoforms of TSEN2 that are produced as a result of alternative splicing events. Isoform 1 seems to carry the active site for 5’-splice site cleavage. Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, which is characterized by progressive microencephaly with epilepsy, extrapyramidal dyskinesia and chorea without spinal cord findings.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4295R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4295R-CY7

Beschreibung: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4295R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4295R-CY3

Beschreibung: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-7417R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7417R-CY3

Beschreibung: SAP 155 is a 1,304 amino acid member of the SF3B1 family and contains eleven HEAT repeats. Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 155 is a subunit of the SF3B splicing factor. The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130, SAP 145 and SAP 155. Concomitant with splicing catalysis, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2. This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction. Due to alternative splicing events, various SAP 155 isoforms are produced.

UOM: 1 * 100 µl

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