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Product Image-665-0334

Multiparameter-Messgeräte, tragbar, U-50 Serie

Lieferant: HORIBA
Beschreibung: Diese wasserdichten Messgeräte können mit einem einzigen Sensor bis zu 11 Parameter gleichzeitig messen und anzeigen. Dank ihrer robusten Konstruktion und ihrer vor Ort austauschbaren Sensoren eignen sie sich bestens für den Einsatz im Freien, zum Beispiel bei der Prüfung von Grund- oder Oberflächenwasser. Durch ihre kompakte Größe und die Trageschlaufe ist eine einhändige Bedienung möglich.

Product Image-141-1591

SlimLine PLW 7111 Laborgläserspüler

Lieferant: MIELE
Beschreibung: Die Laborspüler PLW 7111 SlimLine bieten eine umfassende und systematische Lösung für die analysenreine Aufbereitung von Laborglaswaren.

Image Unavailable-BOSSBS-6634R-A680

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6634R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-A680
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-CY5

Anti-XPC Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6634R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-CY5
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A647

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-6634R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-A647
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Product Image-171-2709

Kartusche für Wasserreinigungssystem, Prolabo

Artikel-Nr: (171-2709)
Lieferant: VWR Collection
Beschreibung: FLODEM single-use demineralisation cartridge, VWR®
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-6634R-CY3

Anti-XPC Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-6634R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-CY3
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-HRP

Anti-XPC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-6634R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-HRP
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-D9564-10MG

4',6-Diamidin-2-phenylindol-dilactat (DAPI) ≥98% (durch HPLC) Verwendung in der nuklearen Färbung, Sigma-Aldrich®

Artikel-Nr: (D9564-10MG)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : D9564-10MG
Beschreibung: A high sensitivity dye used to detect single nucleic acid molecules. DAPI has been shown to detect a single DNA molecule in solution, and to detect femtograms of DNA in single cells and chloroplasts.
UOM: 1 * 10 mg
Image Unavailable-15343-50MG

Lead ionophore IV, Selectophore™ Ionophor, Supelco®

Artikel-Nr: (15343-50MG)
Lieferant: Merck
Hersteller Artikel Nummer : 15343-50MG
Beschreibung: Lead ionophore IV (tert-Butylcalix[4]arene-tetrakis(N,N-dimethylthioacetamide)), was used in the fabrication of robust potentiometric ion sensors
UOM: 1 * 50 mg
Image Unavailable-COMAPX33L

Immersion probe

Artikel-Nr: (COMAPX33L)
Lieferant: COMARK
Hersteller Artikel Nummer : PX33L
Beschreibung: The PX33L Integral Plug Probe is a general purpose penetration probe that connects directly to a thermometer for single-handed temperature taking.
UOM: 1 * 1 ST
Product Image-MFLX76000-02

Masterflex® Single-Use Replacement Pump Heads for Quattroflow Pump Systems

Lieferant: Avantor Fluid Handling
Beschreibung: Halten Sie Ihr Quattroflow™-Pumpensystem mit diesen hochwertigen Ersatzpumpenköpfen am Laufen.

Image Unavailable-SH31141.01

Natriumchlorid-Lösung 2 M, in single-use containers, HyClone™ für Bioverfahrenstechnik

Lieferant: HyClone products (Cytiva)
Beschreibung: HyClone™ NaCl solutions in single-use bags offer a convenient format for many upstream and downstream bioprocessing applications.

Product Image-ENTEDSU-00-01-00

Dispensing head, Sentry®

Artikel-Nr: (ENTEDSU-00-01-00)
Lieferant: ENTEGRIS
Hersteller Artikel Nummer : DSU-00-01-00
Beschreibung: Designed for use with FluoroPure® single-use HDPE blowmolded drums, this single-use dispense head provides dispensing functions in a single connection.
UOM: 1 * 1 ST
Image Unavailable-21203-25MG-F

Calcium ionophore V ≥95%, Selectophore™ Ionophor, Supelco®

Artikel-Nr: (21203-25MG-F)
Lieferant: Merck
Hersteller Artikel Nummer : 21203-25MG-F
Beschreibung: Calcium ionophore V (K23E1) may be used in fabricating calcium on to the waveguide sensor to understand the selectivity of the specific ion and also measure its concentration.
UOM: 1 * 25 mg
Product Image-734-2954

VWR®, Single-Use Tank Liners, Medical Grade

Lieferant: VWR Collection
Beschreibung: These tank liners are single-use bags with an open top, designed to fit in cylindrical vessels.

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