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Image Unavailable-BOSSBS-3818R-A750

Anti-GDF15/MIC-1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-3818R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3818R-A750
Beschreibung: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterised by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
UOM: 1 * 100 µl
Product Image-BRDY317809

Label Printer, QWERTZ EU with Bluetooth and Workstation PWID Suite, M610

Artikel-Nr: (BRDY317809)
Lieferant: Brady
Hersteller Artikel Nummer : 317809
Beschreibung: Get the durability your work demands.
UOM: 1 * 1 ST

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Product Image-BRDY317793

Label Printer, AZERTY with Bluetooth, M610

Artikel-Nr: (BRDY317793)
Lieferant: Brady
Hersteller Artikel Nummer : 317793
Beschreibung: Get the durability your work demands.
UOM: 1 * 1 ST
Product Image-664-0234

VWR® DO 40, Gelöstsauerstoff-Messgerät

Artikel-Nr: (664-0234)
Lieferant: VWR Collection
Beschreibung: Dieses tragbare Sauerstoffmessgerät mit wartungsfreundlichem galvanischem Sensor ist ein Einsteigergerät für den alltäglichen Einsatz. Konzentrationen in mg/l (ppm) und Sättigung in Prozent können direkt ohne die Verwendung von Tabellen abgelesen werden.
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-10381R-A750

Anti-Smad1 Ser463 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-10381R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10381R-A750
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple Signalling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3860R-CY3

Anti-CHRDL2 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-3860R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-CY3
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3860R-A488

Anti-CHRDL2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-3860R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-A488
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0699R-CY5

Anti-SLC33A1 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-0699R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0699R-CY5
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10381R

Anti-SMAD1 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-10381R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10381R
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3418R-A555

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-3418R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3418R-A555
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10380R-A555

Anti-SMAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-10380R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10380R-A555
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10380R-CY5

Anti-SMAD1 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-10380R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10380R-CY5
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
Product Image-OXNTMDIP-LSK114

MinION™ Mk1D DNA/RNA Sequencing Device

Lieferant: Oxford Nanopore Technologies
Beschreibung: MinION™ – Ihr persönlicher, tragbarer DNA- und RNA-Sequenzer.

New Product

Image Unavailable-BOSSBS-1475R-A488

Anti-Gremlin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1475R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1475R-A488
Beschreibung: Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1475R-A680

Anti-Gremlin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-1475R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1475R-A680
Beschreibung: Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).
UOM: 1 * 100 µl
Product Image-MFLX75501-12

Flexible Impeller Self-Priming Non-Metallic Pumps

Artikel-Nr: (MFLX75501-12)
Lieferant: Avantor Fluid Handling
Hersteller Artikel Nummer : 75501-12
Beschreibung: Pumps fluids in applications where durability is needed—the 12 VDC models are ideal for remote/portable use.
UOM: 1 * 1 ST

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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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