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Product Image-BRDY815718

Signs, S safety sign

Beschreibung: A comprehensive range of Emergency Escape and First Aid signs which help comply with current legislation.
Artikel-Nr: BRDY815718
UOM: 1 * 1 ST
Hersteller Artikel Nummer : 815718
Lieferant: Brady
Image Unavailable-BOSSBS-3818R-A555

Anti-GDF15 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Beschreibung: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Artikel-Nr: BOSSBS-3818R-A555
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-3818R-A555
Lieferant: Bioss
Image Unavailable-BOSSBS-3818R-A647

Anti-GDF15 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Beschreibung: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Artikel-Nr: BOSSBS-3818R-A647
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-3818R-A647
Lieferant: Bioss
Image Unavailable-BOSSBS-3582R-A680

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Artikel-Nr: BOSSBS-3582R-A680
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-3582R-A680
Lieferant: Bioss
Image Unavailable-BOSSBS-3582R-A350

Anti-T1 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Beschreibung: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Artikel-Nr: BOSSBS-3582R-A350
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-3582R-A350
Lieferant: Bioss
Image Unavailable-BOSSBS-1778R-A680

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Beschreibung: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Artikel-Nr: BOSSBS-1778R-A680
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-1778R-A680
Lieferant: Bioss
Image Unavailable-BOSSBS-1778R-CY7

Anti-GATA4 Rabbit Polyclonal Antibody (Cy7®)

Beschreibung: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Artikel-Nr: BOSSBS-1778R-CY7
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-1778R-CY7
Lieferant: Bioss
Image Unavailable-BOSSBS-1778R-CY3

Anti-GATA4 Rabbit Polyclonal Antibody (Cy3®)

Beschreibung: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Artikel-Nr: BOSSBS-1778R-CY3
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-1778R-CY3
Lieferant: Bioss
Image Unavailable-BOSSBS-6117R-CY5.5

Anti-TR1 Rabbit Polyclonal Antibody (Cy5.5®)

Beschreibung: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Artikel-Nr: BOSSBS-6117R-CY5.5
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-6117R-CY5.5
Lieferant: Bioss
Image Unavailable-BOSSBS-6978R

Anti-ZNF521 Rabbit Polyclonal Antibody

Beschreibung: Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.
Artikel-Nr: BOSSBS-6978R
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-6978R
Lieferant: Bioss
Image Unavailable-BOSSBS-1778R-A647

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Beschreibung: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Artikel-Nr: BOSSBS-1778R-A647
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-1778R-A647
Lieferant: Bioss
Product Image-MFLX07571-52

Masterflex® Pumpen und Zubehör für Dosiersysteme, Avantor®

Beschreibung: Holen Sie das Beste aus Ihrer Masterflex®-Pumpe heraus mit Anschlusskabeln, Ersatzteilen und anderem Zubehör.
Artikel-Nr: MFLX07571-52
UOM: 1 * 1 ST
Lieferant: Avantor Fluid Handling
Image Unavailable-BOSSBS-10380R-CY3

Anti-SMAD1 Rabbit Polyclonal Antibody (Cy3®)

Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Artikel-Nr: BOSSBS-10380R-CY3
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-10380R-CY3
Lieferant: Bioss
Image Unavailable-BOSSBS-10380R-HRP

Anti-SMAD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Artikel-Nr: BOSSBS-10380R-HRP
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-10380R-HRP
Lieferant: Bioss
Image Unavailable-BOSSBS-10380R-A350

Anti-SMAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Artikel-Nr: BOSSBS-10380R-A350
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-10380R-A350
Lieferant: Bioss
Image Unavailable-BOSSBS-3418R-A647

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Artikel-Nr: BOSSBS-3418R-A647
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-3418R-A647
Lieferant: Bioss
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