Sie suchten nach: Uracil

Artikel-Nr: (BOSSBS-2950R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2950R-CY5

Beschreibung: Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6584R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6584R-A647

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-1721R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1721R

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6584R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6584R-A488

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

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Lieferant: Apollo Scientific

Beschreibung: Uridin 99%

Artikel-Nr: (BOSSBS-2950R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2950R-A488

Beschreibung: Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6584R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6584R-A555

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1721R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1721R-CY5.5

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1721R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1721R-CY3

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale

Lieferant: Thermo Fisher Scientific

Beschreibung: 5-Hydroxymethyluracil 98%

Sicherheitsdatenblätter Zertifikate

Artikel-Nr: (BOSSBS-8288R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8288R-HRP

Beschreibung: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8288R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8288R-A555

Beschreibung: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.

UOM: 1 * 100 µl

Sale

Lieferant: Apollo Scientific

Beschreibung: Carmofur

Artikel-Nr: (BOSSBS-1721R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1721R-A750

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8288R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8288R-CY7

Beschreibung: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1721R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1721R-A350

Beschreibung: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

UOM: 1 * 100 µl

Sale