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Anti-MUC5AC Mouse Monoclonal Antibody (CF594) [clone: MUC5AC/917]

Lieferant: Biotium
Beschreibung: Mucin 5AC glycoprotein (MUC5AC) is a 641 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Image Unavailable-BOSSBS-2265R-CY5

Anti-Peptide YY/PYY Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-2265R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2265R-CY5
Beschreibung: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2265R-A488

Anti-Peptide YY/PYY Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-2265R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2265R-A488
Beschreibung: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12950R-A488

Anti-CRTC3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-12950R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12950R-A488
Beschreibung: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12950R-A350

Anti-CRTC3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-12950R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12950R-A350
Beschreibung: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12950R-A555

Anti-CRTC3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-12950R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12950R-A555
Beschreibung: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM: 1 * 100 µl
Image Unavailable-BNC400842-500

Anti-MUC2 Mouse Monoclonal Antibody (CF640R) [clone: MLP/842]

Lieferant: Biotium
Beschreibung: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Image Unavailable-BNUB0842-100

Anti-MUC2 Mouse Monoclonal Antibody (Purified) [clone: MLP/842]

Lieferant: Biotium
Beschreibung: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Image Unavailable-BOSSBS-1445R-CY5.5

Anti-Promotilin Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1445R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1445R-CY5.5
Beschreibung: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1445R-A555

Anti-Promotilin Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-1445R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1445R-A555
Beschreibung: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1445R-HRP

Anti-Promotilin Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Artikel-Nr: (BOSSBS-1445R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1445R-HRP
Beschreibung: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13729R-FITC

Anti-PCLKC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-13729R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13729R-FITC
Beschreibung: PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13729R-A488

Anti-PCLKC Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-13729R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13729R-A488
Beschreibung: PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5797R-A750

Anti-BCL2L12 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-5797R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5797R-A750
Beschreibung: Expressed mainly in breast, thymus, prostate, foetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-BNCB0311-100

Anti-Lewis A Mouse Monoclonal Antibody (Biotin) [clone: 7LE]

Lieferant: Biotium
Beschreibung: Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Image Unavailable-BOSSBS-12485R-A680

Anti-APCL/APC2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-12485R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12485R-A680
Beschreibung: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterised by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.
UOM: 1 * 100 µl
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