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Image Unavailable-BOSSBS-7992R-A647

Anti-CCDC80 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-7992R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7992R-A647
Beschreibung: Promotes cell adhesion and matrix assembly.Tissue specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-FITC

Anti-HYAL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-1235R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1235R-FITC
Beschreibung: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BNC880311-500

Anti-Lewis A Mouse Monoclonal Antibody (CF488A) [clone: 7LE]

Lieferant: Biotium
Beschreibung: Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Image Unavailable-BNC040757-500

Anti-KRT7 Mouse Monoclonal Antibody (CF405S) [clone: K72.7]

Lieferant: Biotium
Beschreibung: This antibody recognizes an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7 ) from colon carcinomas (keratin 7-).

Image Unavailable-BOSSBS-10215R-A555

Anti-CHI3L1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-10215R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10215R-A555
Beschreibung: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6051R-CY5

Anti-HPGD Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6051R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6051R-CY5
Beschreibung: Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
UOM: 1 * 100 µl
Product Image-BOSSBS-5797R

Anti-BCL2L12 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-5797R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5797R
Beschreibung: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-BNCB0760-500

Anti-KRT7 Mouse Monoclonal Antibody (Biotin) [clone: KRT7/760]

Lieferant: Biotium
Beschreibung: This antibody recognizes an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7 ) from colon carcinomas (keratin 7-).

Image Unavailable-BNC400311-500

Anti-Lewis A Mouse Monoclonal Antibody (CF640R) [clone: 7LE]

Lieferant: Biotium
Beschreibung: Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Image Unavailable-BOSSBS-10215R-CY3

Anti-CHI3L1 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-10215R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10215R-CY3
Beschreibung: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10215R-FITC

Anti-CHI3L1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-10215R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-10215R-FITC
Beschreibung: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9923R-A680

Anti-UVRAG Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-9923R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9923R-A680
Beschreibung: UVRAG, also known as p63 or DHTX, is a 699 amino acid cytoplasmic protein. UVRAG has been shown to activate the BECN1/PI 3-kinase complex, which promotes autophagy. Autophagy is the degradation of cellular proteins in the lysosomes, and when this pathway is suppressed, cell growth is deregulated. Mutations in the gene encoding UVRAG have been associated with colon cancer, suggesting that UVRAG is also involved in suppressing the proliferation and tumourigenicity of human colon cancer cells. UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells. Ubiquitously expressed, UVRAG is found at highest levels in kidney, lung, liver and brain. UVRAG contains one C2 domain, which is thought to be involved in calcium-dependent phospholipid binding.
UOM: 1 * 100 µl
Image Unavailable-ENZOALX805077C100

Anti-CEACAM5 Mouse Monoclonal Antibody

Artikel-Nr: (ENZOALX805077C100)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ALX805077C100
Beschreibung: CD66e (CEACAM5; CEA) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180'000-200'000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cells of the tongue, esophagus and cervix. CD66e is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
UOM: 1 * 100 µG

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Image Unavailable-BOSSBS-6081R-A680

Anti-PDGFRL Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6081R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6081R-A680
Beschreibung: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-CY7

Anti-HYAL1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-1235R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1235R-CY7
Beschreibung: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12485R-CY3

Anti-APC2 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-12485R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12485R-CY3
Beschreibung: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner’s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.
UOM: 1 * 100 µl
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