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Lieferant: IKA
Beschreibung: Der Hochdruckhomogenisator HPH ist ein Inline-Disperser zur energieeffizienten, kontinuierlichen Herstellung feinster Emulsionen. Im Vergleich zu anderen IKA-Inline-Maschinen basiert die Dispergierwirkung des Hochdruckhomogenisators HPH nicht auf dem Rotor-Stator-Prinzip. Der verbesserte Homogenisierungseffekt wird im Homogenisator durch spontane Entspannung der Flüssigkeit von max. 2000 bar auf Umgebungsdruck erreicht. Bei gleichem Energieeintrag erzeugt der IKA HPH deutlich feinere Emulsionen als herkömmliche Zahnringdispergatoren. Der Einsatz von Hochdruckhomogenisatoren empfiehlt sich, wenn eine Zerkleinerung bis in den Nanometerbereich erforderlich ist. Diese Maschinen erreichen jedoch eine geringere Durchflussleistung als herkömmliche Dispergierer. Der Hochdruckhomogenisator besteht aus einer Hochdruck-Kolbenpumpe und einem nachgeschalteten Homogenisierventil. Der Druckaufbau im HPH erfolgt durch eine oder mehrere Kolbenpumpen, die mithilfe von Keramikkolben einen druckunabhängigen und nahezu pulsationsfreien Volumenstrom gewährleisten. Der gewünschte Homogenisierdruck lässt sich stufenlos einstellen. Der Druckabbau erfolgt in einem einstellbaren Spalt des Homogenisierventils. Der schnelle Druckabfall in einem bewegten Medium führt zu extrem hohen Turbulenzen und Kavitationen, die die Zerkleinerung des Rohprodukts bewirken. Das Maschinendesign kann an kundenspezifische Aufgaben angepasst werden. Der Hochdruckhomogenisator ist in zwei Größen mit einem oder mehreren Kolben unterschiedlichen Ø erhältlich. Diese Parameter bestimmen den maximalen Homogenisierdruck (800 oder 2000 bar) für einen spezifischen Maschinentyp, das minimal zulässige Zuführvolumen (bis zu 10 ml) sowie Homogenisierergebnisse und Durchflusskapazitäten.

Artikel-Nr: (BOSSBS-7689R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7689R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-FITC
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Lieferant: HAMILTON BONADUZ
Beschreibung: pH-Elektroden für spezielle Laboranwendungen, zum Beispiel mikrobiologische Proben, Seren, flache Oberflächen, kleine Probenvolumen, fettige und eiweißhaltige Proben.

Artikel-Nr: (BOSSBS-12927R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12927R-FITC
Beschreibung: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12927R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12927R-A647
Beschreibung: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7689R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-HRP
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7689R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-A647
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12927R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12927R-A680
Beschreibung: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in Signalling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12927R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12927R-A488
Beschreibung: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7689R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-A555
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Artikel-Nr: (32538-100MG)
Lieferant: Merck
Hersteller Artikel Nummer : 32538-100MG
Beschreibung: Pyridaphenthion may be used as a reference standard for the quantification of pyridaphenthion in biological samples using liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry.
UOM: 1 * 100 mg


Artikel-Nr: (BOSSBS-7689R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-A488
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Lieferant: WTW
Beschreibung: Hochwertige, verbesserte Sensortechnologie kombiniert mit modernster Messelektronik. Die Elektroden verfügen über einen Steckkopf, der entweder mit einem IDS-Kabel oder mit einem Funkmodul verbunden werden kann.

Artikel-Nr: (BOSSBS-7689R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-A350
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7689R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7689R-CY3
Beschreibung: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM: 1 * 100 µl


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