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Product Image-1B1634-0.1KU

VWR®, Cod Uracil-DNA glycosylase

Lieferant: VWR Chemicals
Beschreibung: Uracil-DNA glycosylase (UNG), cod is a thermolabile recombinant enzyme produced in <i>E. coli</i> (ung-) using a modified ung gene derived from Atlantic cod. It degrades uracil-containing single- and double-stranded DNA, but not RNA or thymidine-containing DNA, by hydrolysing the N-glycosidic bond between deoxyribose sugar and the base in uracil. This generates alkaline-sensitive apyramidinic sites in the DNA that will be cleaved upon a combination of alkaline conditions and high temperature.

Sicherheitsdatenblätter

Product Image-WAKFWPESK-0003

PYROSTAR™ ES-F Single Test Kit

Lieferant: FUJIFILM WAKO CHEMICALS
Beschreibung: The PYROSTAR™ ES-F series of reagents represent our uniquely endotoxin specific line of Limulus Amebocyte Lysate products, which are formulated to be used either qualitatively as a gel-clot reagent or quantitatively as a Kinetic-Turbidimetric reagent.

Product Image-MFLX76000-01

Masterflex® Single-Use Replacement Pump Heads with EZ-Set for Quattroflow™ Pump Systems, Avantor®

Lieferant: Avantor Fluid Handling
Beschreibung: Keep your Quattroflow™ pump system up and running with these quality replacement pump heads.

Image Unavailable-BOSSBS-1370R-CY5.5

Anti-ATM Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1370R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1370R-CY5.5
Beschreibung: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1370R-A555

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-1370R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1370R-A555
Beschreibung: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Product Image-BRDY065669

Ball valve lockouts, standard

Lieferant: Brady
Beschreibung: These single-piece, easy to use ball valve lockouts are the ideal tool for securing quarter-turn ball valves in the OFF position.

Product Image-MFLX77122-32-CH

Masterflex® Ismatec® Microflex Pumpensysteme mit variabler Drehzahl, Avantor®

Lieferant: Avantor Fluid Handling
Beschreibung: Benutzerfreundliche Pumpen mit geringem Fluss, die reversibles Pumpen, Remote-Start/Stopp und schnelle Schlauchwechsel ermöglichen.

2 year warranty

Product Image-BOHLP1720-16

Temperatursonden, Lemo®, BOLA

Lieferant: Bohlender
Beschreibung: Wird zur Temperaturmessung in aggressiven Flüssigkeiten verwendet. Das Kabel ermöglicht eine flexible Verbindung vom Messgerät zum Medium.

Product Image-MILXMSHAWGE48

Microbiological filtration system, MicropreSure®

Lieferant: Merck
Beschreibung: MicropreSure on-line filtration sampler improves in-process microbiological testing for bottled water. It uses the pressure in tanks or pressurized lines to process and collect samples through a microporous membrane within an enclosed chamber, securely locked without leaks.

Image Unavailable-BOSSBS-1370R-A488

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1370R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1370R-A488
Beschreibung: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Product Image-TB38

Multiple tissue blot, single species

Lieferant: G-Biosciences
Beschreibung: These multiple tissue, single species blots permit researchers to visualise the tissue distribution of their protein in a particular species. These have been successfully used for the analysis of a wide variety of proteins. Each blot has multiple tissue types from either human, mouse or rat species.

Image Unavailable-90030.

5-Carboxyrhodamine 110 succinimidyl ester ≥90% (durch HPLC) Amin-reaktiver fluoreszierender Farbstoff

Artikel-Nr: (90030.)
Lieferant: Biotium
Hersteller Artikel Nummer : 90030
Beschreibung: Amine-reactive form of single isomer carboxyrhodamine 110, useful in DNA sequencing. For many single-dye-labeling applications, the dye is preferred over other green fluorescent dyes including fluorescein and Alexa 488 because of its exceptional photostability and fluorescence insensitivity to pH (4-9).
UOM: 1 * 5 mg
Product Image-DUPOTJ198TWH4X0025

Chemikalienbeständige Overalls, Tyvek® 800 J, Modell TJ 198 Ta

Lieferant: DuPont
Beschreibung: Für diese robuste und dennoch leichte Kleidung wird eine spezielle „Undurchlässigkeitstechnologie“ verwendet, um eine effiziente Barriere gegen viele anorganische Chemikalien auf Wasserbasis und in niedrigen Konzentrationen (auch unter Druck) sowie Gefahrenpartikel geringer Größe zu erzielen. Das Gewebe ist zudem öl-abweisend.

Image Unavailable-BOSSBS-1370R-A680

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-1370R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1370R-A680
Beschreibung: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Product Image-460-3237

VWR®, Blöcke für Blockthermostate

Lieferant: VWR Collection
Beschreibung: Solid blocks: For use as a low temperature hotplate or for custom drilling.

Product Image-620-1722

VWR®, Fühlerlose, elektronische Thermometer

Artikel-Nr: (620-1722)
Lieferant: VWR Collection
Beschreibung: Diese digitalen Thermometer sind für hochfeuchte Umgebungen geeignet und eine gute Alternative zu Quecksilbermodellen. Mit der Reset-Taste wird ein neuer Überwachungszeitraum festgelegt.
UOM: 1 * 1 ST
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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