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Image Unavailable-BOSSBS-6125R-A750

Anti-p95 NBS1 Ser343 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-6125R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6125R-A750
Beschreibung: Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability.
UOM: 1 * 100 µl
Image Unavailable-D9564-10MG

4',6-Diamidin-2-phenylindol-dilactat (DAPI) ≥98% (durch HPLC) Verwendung in der nuklearen Färbung, Sigma-Aldrich®

Artikel-Nr: (D9564-10MG)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : D9564-10MG
Beschreibung: A high sensitivity dye used to detect single nucleic acid molecules. DAPI has been shown to detect a single DNA molecule in solution, and to detect femtograms of DNA in single cells and chloroplasts.
UOM: 1 * 10 mg
Product Image-273-0148

Planflansch-Becher, DURAN®

Lieferant: DWK Life Sciences
Beschreibung: DURAN® Borosilikatglas 3.3, klar, mit Labor-Planschliff (DN) und Nut für Vakuumanwendungen. Maximaler Betriebsdruck bei 250 °C: 0,5 bar.

Image Unavailable-7283-02

Weitporiges Butyl-(C₄)-Umkehrphasenmedium, J.T. Baker® BAKERBOND®

Lieferant: Avantor
Beschreibung: Die präparative Befüllung ist für die Verwendung bei niedrigem Druck mit einer peristaltischen Pumpe vorgesehen.

Image Unavailable-BOSSBS-6124R-A647

Anti-NBN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-6124R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-A647
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6124R-HRP

Anti-NBN Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-6124R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-HRP
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-VEPA3FSKS610506

Single Use Test Packs, Bowie and Dick Type

Artikel-Nr: (VEPA3FSKS610506)
Lieferant: VP Medical Packaging
Hersteller Artikel Nummer : 3FSKS610506
Beschreibung: Sterilisationsindikator, Bowie-dick single use test pack (prime-pack)
UOM: 1 * 50 ST

New Product


Image Unavailable-SH30566.01

Natriumhydroxid-Lösung 0.5 N (0.5 M), in single-use containers, HyClone™ für Bioverfahrenstechnik

Lieferant: HyClone products (Cytiva)
Beschreibung: HyClone™ NaOH solutions in single-use bags offer a convenient format to effectively modify pH and properly care for and clean your chromatography resins.

Image Unavailable-15343-50MG

Lead ionophore IV, Selectophore™ Ionophor, Supelco®

Artikel-Nr: (15343-50MG)
Lieferant: Merck
Hersteller Artikel Nummer : 15343-50MG
Beschreibung: Lead ionophore IV (tert-Butylcalix[4]arene-tetrakis(N,N-dimethylthioacetamide)), was used in the fabrication of robust potentiometric ion sensors
UOM: 1 * 50 mg
Image Unavailable-BOSSBS-6124R-A555

Anti-NBN Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-6124R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-A555
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6124R-CY7

Anti-NBN Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-6124R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-CY7
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Product Image-SARTFT-3-211-055

Qualitative Filterpapiere, nassfest

Lieferant: Sartorius
Beschreibung: Diese qualitativen Filterpapiere werden für analytische Zwecke und Routine-Analysen eingesetzt, wenn keine gravimetrischen Analysen erforderlich sind. Durch ihre Nassfestigkeit können sie für die Druck- oder Vakuumfiltration verwendet werden. Sie werden aus Edelzellstoffen und Linters mit einem Gehalt von mehr als 95% α-Cellulose hergestellt und sind mit einem Aschegehalt von < 0,1 % sehr rein.

Image Unavailable-BOSSBS-6124R-A750

Anti-p95 NBS1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-6124R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-A750
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6124R-FITC

Anti-NBN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-6124R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-FITC
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-CONTMGMP0001

Single use microfibre products, MicroGenesis™

Artikel-Nr: (CONTMGMP0001)
Lieferant: CONTEC
Hersteller Artikel Nummer : MGMP0001
Beschreibung: These single use microfibre pads feature synthetic construction for the effective removal of both gross contamination and fine particles. Conveniently designed to provide a new pad for each new use, they are compatible with most existing hardware.
UOM: 1 * 140 ST
Product Image-MFLX31201-66

Masterflex® Einweg-hygienische Dichtung, TPE, Avantor®

Lieferant: Avantor Fluid Handling
Beschreibung: Stellen Sie sicher, dass Ihre Hygiene-Flüssigkeitsleitung sicher abgedichtet ist.

Zertifikate 3A Sanitary approval

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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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