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Image Unavailable-BOSSBS-5473R-A750

Anti-Tau protein Ser416 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-5473R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5473R-A750
Beschreibung: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilisation. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
UOM: 1 * 100 µl
Product Image-ENZOENZKIT1270001

E. coli host cell protein ELISA kit

Artikel-Nr: (ENZOENZKIT1270001)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ENZKIT1270001
Beschreibung: Sensitive (30 ng/ml) ELISA for the quantitative determination of host cell protein contamination in bulk products expressed in E. coli expression systems.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-11417R-A555

Anti-MC4R Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-11417R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11417R-A555
Beschreibung: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
UOM: 1 * 100 µl
Product Image-SOLUL-8109-1000

TriLink® CleanCap® M6 EPO mRNA (N1MePsU)

Lieferant: TriLink BioTechnologies
Beschreibung: <p>EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA <em>in vivo</em> resulted in significant increases of both reticulocyte counts and hematocrits.</p>

New Product

Product Image-SOLUL-7209-100

TriLink® CleanCap® EPO mRNA (5moU)

Lieferant: TriLink BioTechnologies
Beschreibung: EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko <em>et al.</em> showed that transfection of EPO mRNA <em>in vivo</em> resulted in significant increases of both reticulocyte counts and hematocrits.

New Product

Image Unavailable-BOSSBS-11417R-HRP

Anti-MC4R Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-11417R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11417R-HRP
Beschreibung: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
UOM: 1 * 100 µl
Image Unavailable-AGLS200133

BL21 competent cells

Lieferant: AGILENT
Beschreibung: BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

Image Unavailable-BOSSBS-11395R-FITC

Anti-VAMP8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-11395R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11395R-FITC
Beschreibung: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11395R-A555

Anti-VAMP8 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-11395R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11395R-A555
Beschreibung: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11395R-A647

Anti-VAMP8 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-11395R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11395R-A647
Beschreibung: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9474R

Anti-NFAT5 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-9474R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9474R
Beschreibung: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9474R-A647

Anti-NFAT5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-9474R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9474R-A647
Beschreibung: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9474R-CY5

Anti-NFAT5 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-9474R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9474R-CY5
Beschreibung: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
UOM: 1 * 100 µl
Image Unavailable-BNUB0530-500

Anti-BCL2 Mouse Monoclonal Antibody (Purified) [clone: 124]

Lieferant: Biotium
Beschreibung: This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.

Image Unavailable-BOSSBS-0315R-A555

Anti-FGL2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-0315R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0315R-A555
Beschreibung: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.
UOM: 1 * 100 µl
Image Unavailable-BNC471234-500

Anti-BCL2 Mouse Monoclonal Antibody (CF647) [clone: 100/D5 124]

Lieferant: Biotium
Beschreibung: This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.

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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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