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Artikel-Nr: (ORIGTP313207M)
Lieferant: OriGene
Hersteller Artikel Nummer : TP313207M
Beschreibung: This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation.
UOM: 1 * 100 µl

New Product


Artikel-Nr: (ENZOENZKIT1270001)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ENZKIT1270001
Beschreibung: Sensitive (30 ng/ml) ELISA for the quantitative determination of host cell protein contamination in bulk products expressed in E. coli expression systems.
UOM: 1 * 1 KIT


Artikel-Nr: (BOSSBS-13070R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13070R-CY3
Beschreibung: The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.
UOM: 1 * 100 µl


Lieferant: AGILENT
Beschreibung: BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

Artikel-Nr: (BOSSBS-13706R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13706R-CY7
Beschreibung: The calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.
UOM: 1 * 100 µl


Artikel-Nr: (ORIGTP790148)
Lieferant: OriGene
Hersteller Artikel Nummer : TP790148
Beschreibung: <p>Purified recombinant protein of <em>S. pyogenes</em> Cas9 endonuclease (Cas9) containing Simian virus 40 (SV40) T antigen nuclear localisation sequence (NLS) on the N- and C- termini of the protein., with N-terminal HIS tag, expressed in <em>E.coli</em>, sterile-filtered, suitable for cell culture.</p>
UOM: 1 * 500 Pmole

New Product


Artikel-Nr: (BOSSBS-13070R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13070R
Beschreibung: The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.
UOM: 1 * 100 µl


Artikel-Nr: (ENZOBMLSE1800010)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : BMLSE1800010
Beschreibung: Produced in <i>E.coli</i>. Active Matrix Metalloproteinase-1 (MMP-1, interstitial collagenase, fibroblast collagenase) catalytic domain from human cDNA, expressed in <i>E.coli</i>.
UOM: 1 * 10 µG


Artikel-Nr: (BOSSBS-8460R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8460R-A750
Beschreibung: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6548R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6548R
Beschreibung: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3860R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-A750
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterised as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3860R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3860R-A555
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12136R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12136R-A680
Beschreibung: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12136R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12136R-A750
Beschreibung: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl


Artikel-Nr: (ORIGTP710017)
Lieferant: OriGene
Hersteller Artikel Nummer : TP710017
Beschreibung: Recombinant protein of human activating transcription factor 2 (ATF2), full length, with C-terminal polyhistidine tag, expressed in sf9 cells.
UOM: 1 * 20 µG

New Product


Artikel-Nr: (BOSSBS-13070R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13070R-CY7
Beschreibung: The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.
UOM: 1 * 100 µl


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