Sie suchten nach: PX-866

Artikel-Nr: (BOSSBS-12406R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12406R-CY7

Beschreibung: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12249R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12249R-HRP

Beschreibung: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor and facilitate its transport to lysosome, thereby contributing to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes and they likewise associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multi-subunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12248R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12248R-A750

Beschreibung: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-12406R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12406R-CY5

Beschreibung: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12248R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12248R-HRP

Beschreibung: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

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Lieferant: KINEMATICA

Beschreibung: Mühle

Lieferant: OMEGA BIO-TEK

Beschreibung: Das Mag-Bind® PX Blood RNA Kit ermöglicht die Isolierung von Gesamt-RNA aus 2,5 ml Vollblut, das in PAXgene® Blood RNA Röhrchen aufbewahrt wurde. Stabilisierte Blutproben werden zunächst abzentrifugiert, und die Nukleinsäure-Pellets werden gewaschen und aufgefangen. Nach dem Waschen werden die Nukeidsäure-Pellets in einem speziell formulierten Resuspensionspuffer aufgelöst. An diesem Punkt können die Proben auf 96-Well-Platten transferiert werden, um sie dann in Liquid-Handling-Robotern und magnetischen Prozessoren zu verarbeiten. Hochwertige intakte RNA lässt sich in weniger als 90 Minuten isolieren.

Artikel-Nr: (BOSSBS-12406R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12406R-A488

Beschreibung: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11645R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11645R-A555

Beschreibung: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11645R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11645R-A350

Beschreibung: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11645R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11645R-A680

Beschreibung: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain. The Src family of protein tyrosine kinases act in signal transduction pathways. Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain. In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated. Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src. Fish is likely to be involved in tyrosine kinase Signalling and may have a role in cytoskeletal changes.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11645R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11645R-A647

Beschreibung: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11568R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11568R

Beschreibung: HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.

UOM: 1 * 100 µl

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Artikel-Nr: (412-0516)

Lieferant: KINEMATICA

Hersteller Artikel Nummer : 35010021

Beschreibung: Die Mühle mit leistungsstarkem Motor eignet sich für alle Laboranwendungen mit trockenen Substanzen. Die Mahlkammer mit festem Trichter und Drehschieber zur Probenzuführung kann wahlweise mit Hammerschlag- oder Schneid-Mahleinsatz (austauschbar) und Sieben mit Maschenweiten von 0,2 bis max. 6 mm verwendet werden. Die Kammerteile, die direkt mit den Proben in Kontakt kommen, bestehen aus gehärtetem Edelstahl; das Untergestell aus eloxiertem Aluminium verfügt über einen integrierten Tragegriff. Das Mahlgut kann mithilfe von NS 29/32 Normgefäßen (Halteklemme erforderlich) oder Auffangröhrchen aufgefangen werden.

UOM: 1 * 1 ST

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Artikel-Nr: (BOSSBS-12248R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12248R-CY3

Beschreibung: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12248R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12248R-CY7

Beschreibung: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

UOM: 1 * 100 µl

Sale