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Image Unavailable-BOSSBS-13698R-A750

Anti-RAGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-13698R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13698R-A750
Beschreibung: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13698R-HRP

Anti-RAGEF2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-13698R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13698R-HRP
Beschreibung: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-A555

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-2201R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2201R-A555
Beschreibung: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-CY7

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-2201R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2201R-CY7
Beschreibung: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-CY3

Anti-DOCK1 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-7110R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-CY3
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-CY7

Anti-DOCK1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-7110R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-CY7
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3382R-A647

Anti-RASGRF1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-3382R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3382R-A647
Beschreibung: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-A647

Anti-DOCK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-7110R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-A647
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13698R-CY7

Anti-RAGEF2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-13698R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13698R-CY7
Beschreibung: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-FITC

Anti-ARHGEF2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-2201R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2201R-FITC
Beschreibung: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-CY3

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-2201R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2201R-CY3
Beschreibung: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-CY5.5

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-2201R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2201R-CY5.5
Beschreibung: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-HRP

Anti-DOCK1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-7110R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-HRP
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11581R-A555

Anti-RAPGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-11581R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11581R-A555
Beschreibung: PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-A680

Anti-DOCK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-7110R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-A680
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7110R-A488

Anti-DOCK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-7110R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7110R-A488
Beschreibung: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
UOM: 1 * 100 µl
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