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N-Acetyl-L-glutaminsäure ≥99%

Lieferant: Thermo Scientific

Beschreibung: N-Acetyl-L-glutaminsäure ≥99%

Sicherheitsdatenblätter

2-Phosphonomethyl pentanedioic acid ≥97% (durch HPLC)

Artikel-Nr: (ENZOALX550358M005)

Lieferant: ENZO LIFE SCIENCES

Hersteller Artikel Nummer : ALX550358M005

Beschreibung: Potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase (NAALADase), which is a membrane-bound peptidase that hydrolyses N-acetyl-L-aspartate-L-glutamate (NAAG), a major brain peptide.

UOM: 1 * 5 mg

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Ac-Glu(OtBu)-OH 95%

Lieferant: Thermo Scientific

Beschreibung: Ac-Glu(OtBu)-OH 95%

Zertifikate

Anti-FOLH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-2899R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2899R-HRP

Beschreibung: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

UOM: 1 * 100 µl

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N-Acetyl-Asp-Glu-OH

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Glutamate receptor ligand

New Product

S. hygroscopicus recombinant PPT N-acetyltransferase (from E. coli)

Artikel-Nr: (PRSI92-657)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 92-657

Beschreibung: Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant genome can confer resistance to glufosinate herbicide during post-emergent applications.

UOM: 1 * 50 µG

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Anti-FOLH1 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI51-109)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 51-109

Beschreibung: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

UOM: 1 * 250 µl

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Anti-FOLH1 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI25-996)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 25-996

Beschreibung: FOLH1 is a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. A mutation in the gene encoding FOLH1 may be associated with impaired intestinal absorption of dietary folates.It is used as an effective diagnostic and prognostic indicator of prostate cancer.This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants.

UOM: 1 * 50 µG

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Anti-NAGS Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI30-708)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 30-708

Beschreibung: NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

UOM: 1 * 100 µG

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L-Glutamic acid, certified reference material, TraceCERT®, Supelco®

Artikel-Nr: (95436-100MG)

Lieferant: Merck

Hersteller Artikel Nummer : 95436-100MG

Beschreibung: L-Glutamic acid has been used as a reference material in the development of quantitative nuclear magnetic resonance technique to evaluate the purity of organic molecules.

UOM: 1 * 100 mg

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