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Image Unavailable-BOSSBS-2686R-A680

Anti-DKK3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-2686R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2686R-A680
Beschreibung: Antagonises canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6468R-CY5

Anti-KCNJ8 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6468R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6468R-CY5
Beschreibung: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
UOM: 1 * 100 µl
Product Image-PRSI27-061

Anti-APBB2 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI27-061)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 27-061
Beschreibung: APBB2 may modulate the internalization of beta-amyloid precursor protein.The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-3907R-A680

Anti-Legumain Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-3907R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3907R-A680
Beschreibung: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13164R-CY3

Anti-FLNA Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-13164R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13164R-CY3
Beschreibung: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.
UOM: 1 * 100 µl
Image Unavailable-SOCO416.5000

Dispenserpipette, Stepper™ 416

Artikel-Nr: (SOCO416.5000)
Lieferant: Socorex Isba
Hersteller Artikel Nummer : 416.5000
Beschreibung: Einstellbare Pipette für verlässliches Dispensieren und präzise Ergebnisse. Ausgewählte Materialien sorgen für Schlagfestigkeit und eine kompakte Form, was das Risiko für interne Kontaminierung stark reduziert. Die Pipette bietet bis zu 73 Dosierungen mit einer großen Auswahl an 53 verschiedenen Volumen.
UOM: 1 * 1 ST
Product Image-PRSI26-001

Anti-LRP8 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI26-001)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 26-001
Beschreibung: LRP8 is an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL). The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins.This gene encodes an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL). The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-3907R-A647

Anti-LGMN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-3907R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3907R-A647
Beschreibung: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3907R-A488

Anti-LGMN Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-3907R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3907R-A488
Beschreibung: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3907R-A750

Anti-Legumain Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-3907R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3907R-A750
Beschreibung: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7877R-CY7

Anti-NEDD4 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-7877R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7877R-CY7
Beschreibung: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
Image Unavailable-C5548-100MG

Clobetasone butyrate ≥98%

Artikel-Nr: (C5548-100MG)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : C5548-100MG
Beschreibung: Clobetasone butyrate is a corticosteroid. It can be used as a diagnostic assay manufacturing, hematology, histology. Clobetasone butyrate has been used as an internal standard for the quantitative assay of clobetasol propionate. Clobetasone butyrate has been used to analyse its bio-concentration factor (BCF) in cyprinus carpio. Clobetasone butyrate is a potent topical corticosteroid and is primarily used to treat atopic dermatitis (AD). Low dosage of this drug is used to treat dry eye in sjogrens syndrome.
UOM: 1 * 100 mg
Product Image-PRSI26-221

Anti-NETO2 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI26-221)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 26-221
Beschreibung: NETO2 is a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis.This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis. Alternatively spliced transcript variants have been observed, but they have not been fully characterized.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-7877R-FITC

Anti-NEDD4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-7877R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7877R-FITC
Beschreibung: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7877R-A488

Anti-NEDD4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-7877R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7877R-A488
Beschreibung: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7877R-A350

Anti-NEDD4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-7877R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7877R-A350
Beschreibung: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl
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