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Artikel-Nr: (BOSSBS-11235R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11235R-HRP
Beschreibung: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3048R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3048R-CY7
Beschreibung: Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3048R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3048R-FITC
Beschreibung: Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
UOM: 1 * 100 µl


Artikel-Nr: (AATB21224)
Lieferant: AAT BIOQUEST
Hersteller Artikel Nummer : 21224
Beschreibung: Protonex™ Green 500 PEG12 maleimide is a thiol-reactive, pH-sensitive fluorophore specifically designed for developing pH-responsive bioconjugates to investigate processes such as antibody internalization, endocytosis, and phagocytosis in live cells.
UOM: 1 * 1 mg

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Artikel-Nr: (BOSSBS-3048R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3048R-A750
Beschreibung: Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
UOM: 1 * 100 µl


Lieferant: VWR Collection
Beschreibung: Diese Feuchtebestimmer mit großem farbigem Touchscreen-Display ermöglichen einen benutzerfreundlichen Zugriff auf erweiterte Anwendungen und interne Datenbanken. Der Benutzer hat über symbolgesteuerte Menüs einen intuitiven Zugriff auf die schnelle Programmierung von Trocknungszyklen.

Artikel-Nr: (BOSSBS-6763R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6763R-A647
Beschreibung: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
UOM: 1 * 100 µl


Lieferant: JULABO GmbH
Beschreibung: The powerful and robust CORIO™ laboratory circulators provide the exact temperature, absolute precision, and a wide working temperature range. The CORIO™ CP model is an advanced unit with professional technology for demanding applications and can be used for temperature control of internal or external applications due to the powerful and infinitely adjustable pressure pump. The jet nozzle allows continuous adjustment of the pump stream in the system. These heating circulators are optimised for external temperature applications in combination with jacketed reactors, distillation apparatus, mini-plant applications, photometers, refractometers and can also be used for internal temperature applications of samples and small objects.

Artikel-Nr: (BOSSBS-11235R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11235R-A555
Beschreibung: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11235R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11235R-CY3
Beschreibung: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
UOM: 1 * 100 µl


Artikel-Nr: (YSIA003252)
Lieferant: YSI ENVIRONMENTAL
Hersteller Artikel Nummer : 003252
Beschreibung: YSI 3200 series conductivity cells have built-in thermistors, allowing automatic temperature compensation. All YSI cells are calibrated according to the International Organization of Legal Metrology recommendations 56 and 68.
UOM: 1 * 1 ST


Artikel-Nr: (BOSSBS-6763R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6763R-CY5
Beschreibung: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6763R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6763R-FITC
Beschreibung: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6763R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6763R-A555
Beschreibung: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11235R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11235R-FITC
Beschreibung: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6763R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6763R-CY7
Beschreibung: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
UOM: 1 * 100 µl


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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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