Sie suchten nach: Methyl-trans-4-hydroxycyclohexancarboxylat 

Lieferant: Merck

Beschreibung: EMSURE® grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE® provides worldwide best and most extensive product specifications. We declare our EMSURE® range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.

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Lieferant: Thermo Fisher Scientific

Beschreibung: TRACE™ TR-FAME GC columns are ideal for separation of cis or trans isomers and fatty acid methyl esters (FAMEs) with various degrees of unsaturation.

Artikel-Nr: (786-082)

Lieferant: G-Biosciences

Hersteller Artikel Nummer : 786-082

Beschreibung: Ideal for enzyme-antibody crosslinking.

UOM: 1 * 8 ST

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Lieferant: AAT BIOQUEST

Beschreibung: Sulfo-SMCC is the water-soluble version of SMCC.

Artikel-Nr: (573115-50)

Lieferant: Merck Millipore (Calbiochem‎)

Hersteller Artikel Nummer : 573115-50

Beschreibung: SMCC, Water-Soluble, a water-soluble derivative of SMCC.

UOM: 1 * 50 mg

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Artikel-Nr: (AATB4503)

Lieferant: AAT BIOQUEST

Hersteller Artikel Nummer : 4503

Beschreibung: Compared to SMCC and sulfo-SMCC, SMCC Plus has enhanced water solubility and crosslinking efficiency.

UOM: 1 * 5 mg

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Lieferant: Merck

Beschreibung: Mit ihrer hohen UV-Durchlässigkeit und niedrigen Partikelanzahl und ihrem geringen Säure- und Basengehalt sowie geringen Verdampfungsrückständen eignen sich LiChrosolv® Lösungsmittel ideal für reproduzierbare Trennungen. Da Trennungen in der analytischen HPLC normalerweise unter Gradientenbedingungen stattfinden, bieten wir Lösungsmittel sowohl in der Güteklasse „Gradient Grade“ als auch in „Isocratic Grade“ und damit eine Möglichkeit, den Gradienteneffekt des beteiligten Lösungsmittels auf ein Minimum zu reduzieren.

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Lieferant: Thermo Fisher Scientific

Beschreibung: Thermo Scientific Pierce Premium Grade Sulfo-SMCC is our highest quality formulation of amine-to-sulfhydryl crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

Lieferant: Thermo Fisher Scientific

Beschreibung: Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).

Artikel-Nr: (PIERA39268)

Lieferant: Thermo Fisher Scientific

Hersteller Artikel Nummer : A39268

Beschreibung: Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).

UOM: 1 * 20 mg

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Artikel-Nr: (PRSI56-286)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 56-286

Beschreibung: RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. RBL2 may act as a tumor suppressor.

UOM: 1 * 400 µl

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Artikel-Nr: (573114-100)

Lieferant: Merck Millipore (Calbiochem‎)

Hersteller Artikel Nummer : 573114-100

Beschreibung: Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.
Reacts with primary amines and sulfhydryl groups.

UOM: 1 * 100 mg

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Lieferant: MP Biomedicals

Beschreibung: Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

Lieferant: AAT BIOQUEST

Beschreibung: SMCC is a non-cleavable and membrane permeable crosslinker with a spacer arm of 8.3 Å. It contains an amine-reactive succinimidyl ester (SE) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7 to 9 to form stable amide bonds. Maleimides react with sulfhydryl groups at pH 6.5 to 7.5 to form stable thioether bonds. The SE group of SMCC is reacted with lysine residues on the carrier protein, converting them to reactive maleimides. SMCC is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.

Artikel-Nr: (PIER22360)

Lieferant: Thermo Fisher Scientific

Hersteller Artikel Nummer : 22360

Beschreibung: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

UOM: 1 * 50 mg

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Artikel-Nr: (PIERA35394)

Lieferant: Thermo Fisher Scientific

Hersteller Artikel Nummer : A35394

Beschreibung: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

UOM: 1 * 10 mg

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