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Image Unavailable-BOSSBS-6124R-A680

Anti-p95 NBS1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6124R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-A680
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Product Image-181-0236

VWR® Kompakte Vakuumpumpen für Filtration und Festphasenextraktion

Lieferant: VACUUBRAND
Beschreibung: Vakuumfiltration ist eine der häufigsten Anwendungen zur Probenvorbereitung in Chemie, Mikrobiologie, Abwasserkontrolle und anderen analytischen Prozessen. Die Membranpumpen VP 100 und VP 100 C bieten eine kompakte, leistungsstarke und benutzerfreundliche Lösung, die sich perfekt für Einzel- und Mehrfachfiltrationen eignet.

Product Image-620-2692

VWR®, Wetterstation

Artikel-Nr: (620-2692)
Lieferant: VWR Collection
Beschreibung: Diese Wetterstation wird insbesondere in Labors, in der Landwirtschaft, in Büros und an Universitäten verwendet. Mit internem Temperaturfühler.
UOM: 1 * 1 ST
Product Image-SENA0096647494821

Low temperature Pt100 probe

Artikel-Nr: (SENA0096647494821)
Lieferant: SenseAnywhere
Hersteller Artikel Nummer : 0096647494821
Beschreibung: This smart probe featuring a digital SenseAnywhere Bus interface has been especially designed to be used in ultra-low environments for monitoring cryogenic applications down to -200 °C. The class A wire wound ceramic Pt100 sensor ensures accurate measurements over a wide temperature range. Due to the digital interface this probe with its own serial number and integrated electonics can be calibrated. Calibrated SAB sensors can be easily hot swapped offering a big advantage and cost savings for recalibration of sensors.
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-6124R-FITC

Anti-NBN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-6124R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-FITC
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6124R-A750

Anti-p95 NBS1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-6124R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6124R-A750
Beschreibung: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM: 1 * 100 µl
Product Image-1.07736.1000

Silica gels for TLC and PLC plates, standardised

Lieferant: Merck
Beschreibung: Selection of standardised and modified silica gels that are available in many granulations and supplied from one single source, dedicated to chromatography. Standardised silica gels are widely used in separation processes to purify valuable compounds in ton quantities.

Sicherheitsdatenblätter

Product Image-664-0511

Gelöst-Sauerstoffsensoren, CellOx® / DurOx®

Lieferant: WTW
Beschreibung: Galvanische Sauerstoffsensoren für den Labor- (CellOx®) oder den Feldeinsatz (DurOx®).

Product Image-620-1984

Temperatur- und Feuchtigkeitssonden für Datenlogger

Lieferant: Testo
Beschreibung: Verwenden Sie die Feuchte-/Temperaturfühler (mit einem entsprechenden Messgerät) zur zuverlässigen Messung von relativer Feuchte und Temperatur. Der Feuchtigkeitssensor ist langlebig und rückführbar auf internationale Feuchtigkeitsstandards wie ILAC, PTB und NIST. So können Sie sich auch nach jahrelangem Einsatz auf zuverlässige und korrekte Messergebnisse verlassen.

Product Image-620-2643

VWR® TD20, TD21, TD22, Universelle, wasserdichte Präzisionsthermometer

Lieferant: VWR Collection
Beschreibung: Wasserdichte, kalibrierbare Thermometer für hochpräzise Messungen in Flüssigkeiten und in der Luft oder zur Messung von Kerntemperaturen (mit Einstechfühler); Sensorgriff und Kabeltemperaturbereich bis 250 °C (Dauergebrauchstemperatur von 230 °C). Ideal für Laboratorien, Qualitätssicherung, Service, Lebensmittel, etc.

Product Image-PAWBEVSS-PVC8.74

OmniTop Sample Tubes® Exact Volume Sampling System (EVSS)

Lieferant: Avantor Fluid Handling
Beschreibung: Optimieren Sie Ihre Probenahmeprozesse mit den Exact Volume Sampling Systems (EVSS) von OmniTop Sample Tubes®

Image Unavailable-SGEA09262015

SGE OptChem™ Single Taper Inlet Liners

Lieferant: Trajan Scientific and Medical
Beschreibung: SGE OptChem™ GC inlet liner provide optimal performance with advanced coating technologies in an easy to use format for GC and GCMS.

Product Image-663-0356

VWR® pHenomenal® IDP 761-C, Leitfähigkeitsmesszelle

Artikel-Nr: (663-0356)
Lieferant: VWR Collection
Beschreibung: Diese Leitfähigkeits-/Temperaturmesszelle vom Typ IDP (Intelligent Digital Probe) kann mit den Multiparameter-Messgeräten pHenomenal® MD 8000 H und MD 8000 L verwendet werden.
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-11332R-CY3

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-11332R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11332R-CY3
Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Product Image-METO1WD18S

Shelving systems, direct wall mounts

Lieferant: Metro International
Beschreibung: Direct wall mount brackets allow the installation of wire or solid shelves directly onto a wall surface. Each brackets consists of one shelf support and mounting plate, with two shelf collar caps. Use single support at shelf ends and double support for adjoining shelves.

Image Unavailable-WTWO472103

Universal Monitor, DIQ/S 281

Artikel-Nr: (WTWO472103)
Lieferant: WTW ONLINE
Hersteller Artikel Nummer : 472103
Beschreibung: Universal monitor DIQ/S 281. The new system 281 - the digital and cost-efficient single parameter measuring point with proven IQ Sensor Net technology and IQ sensors for the standard parameters. Low-cost alternative to analog measuring points
UOM: 1 * 1 ST

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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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