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Image Unavailable-BOSSBS-6634R-FITC

Anti-XPC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-6634R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-FITC
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-99311-0.1ML-F

Potassium ionophore I - cocktail A, Selectophore™ Material für Ionensensoren, Supelco®

Artikel-Nr: (99311-0.1ML-F)
Lieferant: Merck
Hersteller Artikel Nummer : 99311-0.1ML-F
Beschreibung: Ready-to-use ion selective liquid for the preparation of microelectrodes in micropipettes
UOM: 1 * 0,1 mL
Image Unavailable-BOSSBS-6634R-CY5

Anti-XPC Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6634R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-CY5
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A647

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-6634R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6634R-A647
Beschreibung: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-81153-100MG

Poly(dimethylsiloxane) analytical standard, for GPC

Artikel-Nr: (81153-100MG)
Lieferant: Merck
Hersteller Artikel Nummer : 81153-100MG
Beschreibung: Poly(dimethylsiloxane) [PDMS] is a polymer. It is a stable silicone rubber. It has been used as ion selective membrane for ion-sensitive field-effect transistors, as spring material in accelerometers, elastomer on a tactile sensor and as flexible encapsulation material in decouple sensors.
UOM: 1 * 100 mg
Product Image-628-3139

Fühler für 445

Lieferant: Testo
Beschreibung: Staurohr, zum Messen der Fließgeschwindigkeit, 1...+100 m/s, Ø×L: 7×300 mm

Product Image-171-2709

Kartusche für Wasserreinigungssystem, Prolabo

Artikel-Nr: (171-2709)
Lieferant: VWR Collection
Beschreibung: FLODEM single-use demineralisation cartridge, VWR®
UOM: 1 * 1 ST
Product Image-SCOI285103553

Platinelektrode, ScienceLine

Artikel-Nr: (SCOI285103553)
Lieferant: SI Analytics
Hersteller Artikel Nummer : 285103553
Beschreibung: Einzel-Platinelektrode, mit Glasschaft und ringförmigem Sensor (Ø 6 mm). Für Titrationsanwendungen.
UOM: 1 * 1 ST
Image Unavailable-D9564-10MG

4',6-Diamidin-2-phenylindol-dilactat (DAPI) ≥98% (durch HPLC) Verwendung in der nuklearen Färbung, Sigma-Aldrich®

Artikel-Nr: (D9564-10MG)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : D9564-10MG
Beschreibung: A high sensitivity dye used to detect single nucleic acid molecules. DAPI has been shown to detect a single DNA molecule in solution, and to detect femtograms of DNA in single cells and chloroplasts.
UOM: 1 * 10 mg
Product Image-665-0334

Multiparameter-Messgeräte, tragbar, U-50 Serie

Lieferant: HORIBA
Beschreibung: Diese wasserdichten Messgeräte können mit einem einzigen Sensor bis zu 11 Parameter gleichzeitig messen und anzeigen. Dank ihrer robusten Konstruktion und ihrer vor Ort austauschbaren Sensoren eignen sie sich bestens für den Einsatz im Freien, zum Beispiel bei der Prüfung von Grund- oder Oberflächenwasser. Durch ihre kompakte Größe und die Trageschlaufe ist eine einhändige Bedienung möglich.

Product Image-INSC513045

Zubehör für DiluFlow gravimetrische Verdünner

Lieferant: INTERSCIENCE
Beschreibung: Verteileranordnung innen für einfache Pumpe (Ø 6,4 mm), Für: Dilu<i>Flow</i>® Elite, Dilu<i>Flow</i>® Pro

Product Image-BEHRB00645358

Accessories for Serial extraction units R 106 S/R 106 S-SK behrotest®

Artikel-Nr: (BEHRB00645358)
Lieferant: BEHR
Hersteller Artikel Nummer : B00645358
Beschreibung: Soxhlet-Extraktionsapparate, WD 30 Monitoring unit with two flow sensors and solenoid valve, as well as cables to connect it to the controller (1.5 m)
UOM: 1 * 1 ST
Image Unavailable-15343-50MG

Lead ionophore IV, Selectophore™ Ionophor, Supelco®

Artikel-Nr: (15343-50MG)
Lieferant: Merck
Hersteller Artikel Nummer : 15343-50MG
Beschreibung: Lead ionophore IV (tert-Butylcalix[4]arene-tetrakis(N,N-dimethylthioacetamide)), was used in the fabrication of robust potentiometric ion sensors
UOM: 1 * 50 mg
Image Unavailable-COMAPX33L

Immersion probe

Artikel-Nr: (COMAPX33L)
Lieferant: COMARK
Hersteller Artikel Nummer : PX33L
Beschreibung: The PX33L Integral Plug Probe is a general purpose penetration probe that connects directly to a thermometer for single-handed temperature taking.
UOM: 1 * 1 ST
Image Unavailable-SGWAW2T808004

Water leak detectors

Lieferant: EVOQUA WATER TECHNOLOGIES
Beschreibung: In case of leakage, a sensor activates a solenoid valve to shut down the water supply.

Product Image-INSC503105

Gravimetric diluter, DiluFlow® Elite

Lieferant: INTERSCIENCE
Beschreibung: Dilu<i>Flow</i>® Elite automatically dilutes in seconds a solid sample with the appropriate weight of diluent with full traceability. Programmable and connectable with up to 6 diluents.

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