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Image Unavailable-BOSSBS-6165R-A488

Anti-HRAS Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-6165R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-A488
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1964R-HRP

Anti-KLK3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-1964R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1964R-HRP
Beschreibung: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1964R-CY5

Anti-KLK3 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-1964R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1964R-CY5
Beschreibung: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Product Image-1.00934.0001

HPTLC- und DC-Platten, Kieselgel 60, MS-Qualität

Lieferant: Merck
Beschreibung: Die Kopplung von DC-Platten und Massenspektrometrie ist ein neues Gebiet, das einen großen Beitrag zum Fortschritt der Planarchromatographie leisten wird. Die Platten in MS-Qualität sind viel reiner als Standard-DC/HPTLC-Platten und bieten eine höhere Empfindlichkeit und reduzierte Hintergrundsignale. Dies ermöglicht die Spurenanalyse mit Massenspektrometriedetektion in einem niedrigeren Nanogrammbereich.

Sicherheitsdatenblätter

Image Unavailable-BOSSBS-5876R

Anti-MMP28 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-5876R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5876R
Beschreibung: Matrix Metalloproteinase 28, also known as epilysin, was first cloned from human skin keratinocytes and described to reflect its role in the remodeling of the epidermis. It was found in testis, as well as heart, brain, placenta, lung, prostate, intestine, and colon. MMP28 was later cloned from human lung and found in lung, kidney, brain, skeletal muscle, and several tumor cell lines. At least three MMP28 transcripts of 2.6, 2.0, and 1.2 kb have been reported possibly representing alternatively spliced forms of MMP28. There are two human sequences (isoform1 and isoform 2) which encode proteins of 520 and 393 amino acids with predicted masses of 58.9 and 44.5 kDa respectively. The mouse sequence contains two inserts of 41 and 39 amino acids respectively, relative to the human sequence. Mouse epilysin has a predicted molecular mass of approx. 70 kDa. Mouse and human epilysin are highly conserved and share 97% identical residues. Epilysin (MMP-28) contains the key domains of the other MMPs: a signal peptide, conserved cysteine-containing prodomain (with a furin cleavage site), conserved histidine-containing catalytic domain, hinge domain, and hemopexin domain. MMP28 has a furin cleavage site, similar to MMP11, and is cleaved by the prohormone convertase family of enzymes. Sequence identity between MMP28 and the other MMPs is low overall. MMP28 is most closely related to MMP19 (39% sequence identity). Recombinant MMP28 degrades casein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-A647

Anti-HRAS Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-6165R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-A647
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-A555

Anti-HRAS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-6165R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-A555
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-A680

Anti-HRAS+KRAS Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6165R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-A680
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9846R-A750

Anti-PauA Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-9846R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9846R-A750
Beschreibung: Plasminogen activator A (PauA) is a Streptococcus uberis protein that functions similarly to proteins within the Staphylokinase/Streptokinase family. Streptococcus uberis is a common cause of infection and inflammatory disease in the bovine udder. Inflammation of breast tissue (mastitis) has been recognised as a serious threat to the welfare of the dairy cow and has a severe economic impact on the dairy industry. S. uberis has been shown to specifically activate bovine and ovine plasminogen and this is mediated by the extracellular protein, plasminogen activator uberis (PauA), which has a molecular mass of around 30 kDa. It has been postulated that activation of plasminogen by PauA may facilitate early bacterial colonization of the lactating gland by promoting the release of nutrients which are likely to be restricted in milk.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R

Anti-HRAS Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-6165R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-FITC

Anti-HRAS Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-6165R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-FITC
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9846R-A680

Anti-PauA Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-9846R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9846R-A680
Beschreibung: Plasminogen activator A (PauA) is a Streptococcus uberis protein that functions similarly to proteins within the Staphylokinase/Streptokinase family. Streptococcus uberis is a common cause of infection and inflammatory disease in the bovine udder. Inflammation of breast tissue (mastitis) has been recognised as a serious threat to the welfare of the dairy cow and has a severe economic impact on the dairy industry. S. uberis has been shown to specifically activate bovine and ovine plasminogen and this is mediated by the extracellular protein, plasminogen activator uberis (PauA), which has a molecular mass of around 30 kDa. It has been postulated that activation of plasminogen by PauA may facilitate early bacterial colonization of the lactating gland by promoting the release of nutrients which are likely to be restricted in milk.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1964R-A488

Anti-KLK3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1964R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1964R-A488
Beschreibung: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-A750

Anti-HRAS+KRAS Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-6165R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-A750
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6165R-CY5.5

Anti-HRAS Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-6165R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6165R-CY5.5
Beschreibung: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2423R-A680

Anti-DLK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-2423R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2423R-A680
Beschreibung: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterised by muscle hypertrophy and decreased fat mass.
UOM: 1 * 100 µl
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