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Malonyl coenzyme A lithium salt ≥90%

Lieferant: Cayman Chemical
Beschreibung: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image Unavailable-07441-10MG

Supelco® Organischer Referenzstandard, Malonyl-L-Carnitin-Lithiumsalz

Lieferant: Merck
Beschreibung: Organic Standard, Malonyl-ʟ-carnitin-Lithiumsalz

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Cerulenin ≥98%, kristalliner Feststoff

Lieferant: Cayman Chemical
Beschreibung: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-12952R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12952R-A680
Beschreibung: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-12954R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12954R-A680
Beschreibung: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Artikel-Nr: (BOSSBS-12954R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12954R-A750
Beschreibung: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-12952R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12952R-A750
Beschreibung: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-500MG

Coenzyme A trilithium salt

Lieferant: Apollo Scientific
Beschreibung: Coenzyme A trilithium salt

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4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilisiertes Pulver

Lieferant: Cayman Chemical
Beschreibung: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilisiertes Pulver

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Coenzyme A sodium salt hydrate ≥95%

Lieferant: Cayman Chemical
Beschreibung: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

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Supelco® Organic Reference Standard, Geranyl Pyrophosphate Lithium Salt

Artikel-Nr: (19533-5MG)
Lieferant: Merck
Hersteller Artikel Nummer : 19533-5MG
Beschreibung: Organic Standard, Geranyl pyrophosphate lithium salt
UOM: 1 * 5 mg
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Riboflavin 5'-monophosphate sodium salt hydrate

Lieferant: Cayman Chemical
Beschreibung: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Zertifikate

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Supelco® Organic Reference Standard, O-Succinyl-ʟ-Carnitine Lithium Salt

Lieferant: Merck
Beschreibung: Organic Standard, O-Succinyl-ʟ-carnitine lithium salt

Image Unavailable-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Artikel-Nr: (55385-10MG)
Lieferant: Merck
Hersteller Artikel Nummer : 55385-10MG
Beschreibung: Organic Standard, 3-Phosphoshikimic acid lithium salt
UOM: 1 * 10 mg
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Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Lieferant: Merck
Beschreibung: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt

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L(+)-Lithiumlactat zur Synthese, Sigma-Aldrich®

Lieferant: Merck
Beschreibung: L(+)-Lithiumlactat zur Synthese, Sigma-Aldrich®

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