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Anti-GFI1B Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-9881R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9881R-A750
Beschreibung: Essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine Signalling pathways. Cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate. Inhibits down-regulation of MYC and MYB as well as the cyclin-dependent kinase inhibitor CDKN1A/P21WAF1 in IL6-treated myelomonocytic cells. Represses expression of GATA3 in T-cell lymphomas and inhibits GATA1-mediated transcription; as GATA1 also mediates erythroid GFI1B transcription, both GATA1 and GFI1B participate in a feedback regulatory pathway controlling the expression of GFI1B gene in erythroid cells. Suppresses GATA1-mediated stimulation of GFI1B promoter through protein interaction. Binds to gamma-satellite DNA and to its own promoter, auto-repressing its own expression. Alters histone methylation by recruiting histone methyltransferase to target genes promoters. Plays a role in heterochromatin formation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R

Anti-UBE2V2 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-9377R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9377R
Beschreibung: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-9377R-CY5.5

Anti-UBE2V2 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-9377R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9377R-CY5.5
Beschreibung: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R-CY7

Anti-UBE2V2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-9377R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9377R-CY7
Beschreibung: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4224R-CY3

Anti-UGT1A9 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-4224R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4224R-CY3
Beschreibung: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11403R-A488

Anti-GNRHR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-11403R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11403R-A488
Beschreibung: Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11403R-HRP

Anti-GNRHR2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-11403R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11403R-HRP
Beschreibung: Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
UOM: 1 * 100 µl
Product Image-SENA0096647494821

Low temperature Pt100 probe

Artikel-Nr: (SENA0096647494821)
Lieferant: SenseAnywhere
Hersteller Artikel Nummer : 0096647494821
Beschreibung: This smart probe featuring a digital SenseAnywhere Bus interface has been especially designed to be used in ultra-low environments for monitoring cryogenic applications down to -200 °C. The class A wire wound ceramic Pt100 sensor ensures accurate measurements over a wide temperature range. Due to the digital interface this probe with its own serial number and integrated electonics can be calibrated. Calibrated SAB sensors can be easily hot swapped offering a big advantage and cost savings for recalibration of sensors.
UOM: 1 * 1 ST
Product Image-BURK5344-0400

Sample bags with closure, SteriBag StandUp

Lieferant: BURKLE
Beschreibung: SteriBag StandUp are sterile sample bags with a stand-up base. The special bottom unfolds as soon as the bag is filled. This makes SteriBag StandUp stable and able to stand on its own without a separate stand or support, leaving both your hands free to take the sample and fill the bag. The wire bracket at the closure keeps the bag open, making it easy and convenient to fill. Can be used for samples available as liquids, powders, solids and pastes; suitable for foods and can be frozen.

Zertifikate

Image Unavailable-BOSSBS-1350R-FITC

Anti-EIF4G2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-1350R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1350R-FITC
Beschreibung: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13258R-A555

Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-13258R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13258R-A555
Beschreibung: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1350R

Anti-DAP5 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-1350R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1350R
Beschreibung: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1350R-CY5

Anti-EIF4G2 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-1350R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1350R-CY5
Beschreibung: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1350R-A488

Anti-EIF4G2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1350R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1350R-A488
Beschreibung: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5357R-A647

Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-5357R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5357R-A647
Beschreibung: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7882R-A647

Anti-UBE2V1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-7882R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7882R-A647
Beschreibung: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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