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Artikel-Nr: (BOSSBS-12030R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12030R-A680
Beschreibung: GPRC6A (G protein-coupled receptor family C group 6 member A) is a 928 amino acid protein encoded by the mouse Gprc6a gene. GPRC6A is a member of the G protein-coupled receptor 3 family. This receptor is activated by both amino acids and extracellular concentration of calcium ions. The activity of GPRC6A is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. GPRC6A senses changes in the extracellular concentration of calcium ions, suggesting that it may mediate extracellular calcium-sensing responses in osteoblasts. Osteocalin stimulates the activity of GPRC6A in the presence of calcium. GPRC6A also acts as a receptor for amino acids, with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine. Its affinity for amino acids suggests that it may act as a regulatory component of the urea cycle. GPRC6A is expressed at high levels in liver, lung, spleen and heart, and at lower levels in kidney, skeletal muscle and brain.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12030R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12030R-CY3
Beschreibung: GPRC6A (G protein-coupled receptor family C group 6 member A) is a 928 amino acid protein encoded by the mouse Gprc6a gene. GPRC6A is a member of the G protein-coupled receptor 3 family. This receptor is activated by both amino acids and extracellular concentration of calcium ions. The activity of GPRC6A is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. GPRC6A senses changes in the extracellular concentration of calcium ions, suggesting that it may mediate extracellular calcium-sensing responses in osteoblasts. Osteocalin stimulates the activity of GPRC6A in the presence of calcium. GPRC6A also acts as a receptor for amino acids, with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine. Its affinity for amino acids suggests that it may act as a regulatory component of the urea cycle. GPRC6A is expressed at high levels in liver, lung, spleen and heart, and at lower levels in kidney, skeletal muscle and brain.
UOM: 1 * 100 µl


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Artikel-Nr: (BOSSBS-12030R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12030R-HRP
Beschreibung: GPRC6A (G protein-coupled receptor family C group 6 member A) is a 928 amino acid protein encoded by the mouse Gprc6a gene. GPRC6A is a member of the G protein-coupled receptor 3 family. This receptor is activated by both amino acids and extracellular concentration of calcium ions. The activity of GPRC6A is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. GPRC6A senses changes in the extracellular concentration of calcium ions, suggesting that it may mediate extracellular calcium-sensing responses in osteoblasts. Osteocalin stimulates the activity of GPRC6A in the presence of calcium. GPRC6A also acts as a receptor for amino acids, with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine. Its affinity for amino acids suggests that it may act as a regulatory component of the urea cycle. GPRC6A is expressed at high levels in liver, lung, spleen and heart, and at lower levels in kidney, skeletal muscle and brain.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12030R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12030R-FITC
Beschreibung: GPRC6A (G protein-coupled receptor family C group 6 member A) is a 928 amino acid protein encoded by the mouse Gprc6a gene. GPRC6A is a member of the G protein-coupled receptor 3 family. This receptor is activated by both amino acids and extracellular concentration of calcium ions. The activity of GPRC6A is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. GPRC6A senses changes in the extracellular concentration of calcium ions, suggesting that it may mediate extracellular calcium-sensing responses in osteoblasts. Osteocalin stimulates the activity of GPRC6A in the presence of calcium. GPRC6A also acts as a receptor for amino acids, with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine. Its affinity for amino acids suggests that it may act as a regulatory component of the urea cycle. GPRC6A is expressed at high levels in liver, lung, spleen and heart, and at lower levels in kidney, skeletal muscle and brain.
UOM: 1 * 100 µl


Artikel-Nr: (ANTIA80100-96)
Lieferant: ANTIBODIES.COM
Hersteller Artikel Nummer : A80100-96
Beschreibung: Rat Ornithine Decarboxylase/ODC1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rat Ornithine Decarboxylase/ODC1 in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Artikel-Nr: (BOSSBS-12211R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12211R
Beschreibung: ZNF148 is a zinc finger transcription factor that is universally expressed. ZBP-89, a Kruppel-like repressor protein, is the silencer element binding factor for Vimentin. ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1). ZBP-89 expression is induced by trans-retinoic acid or butyrate, which also induces terminal differentiation of colon cancer cells. ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53. ZBP-89 also regulates cell proliferation, in part, through its ability to directly bind the p53 protein and retard its nuclear export. Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells.
UOM: 1 * 100 µl


Artikel-Nr: (ANTIA310488-96)
Lieferant: ANTIBODIES.COM
Hersteller Artikel Nummer : A310488-96
Beschreibung: Human Ornithine Aminotransferase ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Ornithine Aminotransferase in serum, plasma, and other biological fluids.
UOM: 1 * 96 Tests

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Artikel-Nr: (ANTIA313718-96)
Lieferant: ANTIBODIES.COM
Hersteller Artikel Nummer : A313718-96
Beschreibung: Mouse Ornithine Decarboxylase/ODC ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Ornithine Decarboxylase/ODC in serum, plasma, and other biological fluids.
UOM: 1 * 96 Tests

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Artikel-Nr: (ANTIA313678-96)
Lieferant: ANTIBODIES.COM
Hersteller Artikel Nummer : A313678-96
Beschreibung: Human Ornithine Decarboxylase/ODC ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Ornithine Decarboxylase/ODC in serum, plasma, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Artikel-Nr: (ANTIA78562-96)
Lieferant: ANTIBODIES.COM
Hersteller Artikel Nummer : A78562-96
Beschreibung: Human Ornithine Decarboxylase/ODC1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Ornithine Decarboxylase/ODC1 in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Artikel-Nr: (PRSI55-401)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 55-401
Beschreibung: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].
UOM: 1 * 400 µl

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Artikel-Nr: (PRSI92-208)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 92-208
Beschreibung: Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyses ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins.
UOM: 1 * 50 µG


Artikel-Nr: (PRSI29-917)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 29-917
Beschreibung: SLC7A4 is involved in the transport of the cationic amino acids (arginine, lysine and ornithine).
UOM: 1 * 50 µG


Artikel-Nr: (PRSI92-034)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 92-034
Beschreibung: Kidney-Type Arginase (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyses the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase.
UOM: 1 * 50 µG


Artikel-Nr: (PRSI30-358)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 30-358
Beschreibung: OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy.This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 100 µG


Artikel-Nr: (PRSI33-182)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 33-182
Beschreibung: This antibody recognises a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
UOM: 1 * 100 µG

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