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Image Unavailable-BOSSBS-1697R-CY3

Anti-DEFA1 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-1697R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1697R-CY3
Beschreibung: Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13140R-CY7

Anti-FANCC Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-13140R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13140R-CY7
Beschreibung: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
UOM: 1 * 100 µl
Image Unavailable-BNC470637-500

Anti-CA9 Mouse Monoclonal Antibody (CF647) [clone: PN-15]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BNC040637-500

Anti-CA9 Mouse Monoclonal Antibody (CF405S) [clone: PN-15]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BOSSBS-0380R-HRP

Anti-MBP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-0380R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0380R-HRP
Beschreibung: Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
UOM: 1 * 100 µl
Image Unavailable-BNC880287-100

Anti-CA9 Mouse Monoclonal Antibody (CF488A) [clone: 66.4.C2]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BOSSBS-5474R-A488

Anti-MBP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-5474R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5474R-A488
Beschreibung: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5474R-CY3

Anti-MBP Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-5474R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5474R-CY3
Beschreibung: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12083R-CY3

Anti-GABRQ Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-12083R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12083R-CY3
Beschreibung: Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.
UOM: 1 * 100 µl
Product Image-USBIH6202-20F

Anti-HMGB2 Mouse Monoclonal Antibody [clone: 3D2]

Artikel-Nr: (USBIH6202-20F)
Lieferant: US Biological
Hersteller Artikel Nummer : H6202-20F
Beschreibung: Anti-HMGB2 Mouse Monoclonal Antibody [clone: 3D2]
UOM: 1 * 50 µG
Image Unavailable-ENZOADIKAPTF120E

Anti-AcK Rabbit Polyclonal Antibody

Artikel-Nr: (ENZOADIKAPTF120E)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ADIKAPTF120E
Beschreibung: Acetylation and methylation of lysine are important post-translational modifications that regulate numerous protein-protein and protein-DNA interactions. Lysine acetylation and methylation involves the transfer of acetylCoA, or one or more methyl groups, to the e-amino group of lysine by modifying enzymes and cofactors. Histones and transcription factors are the primary targets of lysine acetylation and methylation, with either modification capable of inducing gene silencing or expression due to differential regulation of cofactors. For example, varying degrees of mono-, di-, and tri-methylation or acetylation of histone H3 at lysine residue 9 are known to demark distinct chromatin regions during various states of gene activation (methylation) or repression (acetylation).
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-8259R-A680

Anti-DHPS Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-8259R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R-A680
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8259R-A555

Anti-DHPS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-8259R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R-A555
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl
Image Unavailable-ENZOADICSA506E

Anti-MD-2 Rabbit Polyclonal Antibody

Artikel-Nr: (ENZOADICSA506E)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ADICSA506E
Beschreibung: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs recognize different pathogen-associated molecular patterns, thereby linking the innate and adaptive immune responses.
UOM: 1 * 100 µG
Image Unavailable-199311-1G

Tetrabromphenolblau, Sigma-Aldrich®

Lieferant: SIGMA ALDRICH MICROSCOPY
Beschreibung: Tetrabromophenol Blue (TBPB) belongs to the group of sulfonephthalein acid-base indicators. It is employed in the potentiometric titration of the halogens with Hg₂(NO₃)₂. In addition, it has been used as a dye indicator in urine dipstick test to detect proteinuria. In this assay, with increasing concentration of urinary protein, TBPB sequentially changes colour from pale green to blue. Binding of TBPB to proteins is dependent on pH.

Image Unavailable-BOSSBS-6622R-CY5

Anti-GYPC Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6622R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6622R-CY5
Beschreibung: This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
UOM: 1 * 100 µl
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