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Image Unavailable-BOSSBS-7546R-CY3

Anti-BCAM Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-7546R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7546R-CY3
Beschreibung: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13140R-A750

Anti-FANCC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-13140R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13140R-A750
Beschreibung: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
UOM: 1 * 100 µl
Product Image-80132.

CF® Dye Dextran 150000 MW, anionic and fixable

Lieferant: Biotium
Beschreibung: CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 150,000 MW, and contains a formaldehyde-fixable free-amine group.

Product Image-BRDY145580

Gruppen-Verschlusskasten zur Wandmontage, SAFETY REDBOX®

Lieferant: Brady
Beschreibung: Dieser wandmontierbare und tragbare Verschlusskasten ist mit einem Schnelllösesystem ausgestattet, damit er einfach an den jeweiligen Einsatzort transportiert werden kann.

Image Unavailable-BOSSBS-5063R-A488

Anti-GPAM Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-5063R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5063R-A488
Beschreibung: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0380R-HRP

Anti-MBP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-0380R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0380R-HRP
Beschreibung: Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
UOM: 1 * 100 µl
Image Unavailable-BNC040637-500

Anti-CA9 Mouse Monoclonal Antibody (CF405S) [clone: PN-15]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BNC470637-500

Anti-CA9 Mouse Monoclonal Antibody (CF647) [clone: PN-15]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BNC880287-100

Anti-CA9 Mouse Monoclonal Antibody (CF488A) [clone: 66.4.C2]

Lieferant: Biotium
Beschreibung: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Image Unavailable-BOSSBS-5063R-A680

Anti-GPAM Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5063R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5063R-A680
Beschreibung: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5474R-A488

Anti-MBP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-5474R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5474R-A488
Beschreibung: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5474R-CY3

Anti-MBP Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-5474R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5474R-CY3
Beschreibung: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12083R-CY3

Anti-GABRQ Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-12083R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12083R-CY3
Beschreibung: Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.
UOM: 1 * 100 µl
Image Unavailable-40072.

Succinimidyl ester ethidium bromide DNA/RNA Vergleichsfarbstoff

Artikel-Nr: (40072.)
Lieferant: Biotium
Hersteller Artikel Nummer : 40072
Beschreibung: The amine reactive succinimidyl ester of EB (ethidium bromide) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in red fluorescence.
UOM: 1 * 5 mg
Image Unavailable-BOSSBS-6249R-A350

Anti-LCMT1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-6249R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6249R-A350
Beschreibung: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6249R-A488

Anti-LCMT1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-6249R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6249R-A488
Beschreibung: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)
UOM: 1 * 100 µl
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