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Image Unavailable-BNC680783-100

Anti-SILV Mouse Monoclonal Antibody (CF568) [clone: PMEL/783]

Lieferant: Biotium
Beschreibung: Cytotoxic T lymphocytes (CTL's) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

Image Unavailable-BOSSBS-3617R-CY7

Anti-S6K2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-3617R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3617R-CY7
Beschreibung: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3617R-A350

Anti-S6K2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-3617R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3617R-A350
Beschreibung: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3498R-A647

Anti-S6K2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-3498R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3498R-A647
Beschreibung: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
UOM: 1 * 100 µl
Image Unavailable-ENZOADIKAPTF1213E

Anti-Methyl-lysine Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (ENZOADIKAPTF1213E)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ADIKAPTF1213E
Beschreibung: Acetylation and methylation of lysine are important post-translational modifications that regulate numerous protein-protein and protein-DNA interactions. Lysine acetylation and methylation involves the transfer of acetylCoA, or one or more methyl groups, to the e-amino group of lysine by modifying enzymes and cofactors. Histones and transcription factors are the primary targets of lysine acetylation and methylation, with either modification capable of inducing gene silencing or expression due to differential regulation of cofactors. For example, varying degrees of mono-, di-, and tri-methylation or acetylation of histone H3 at lysine residue 9 are known to demark distinct chromatin regions during various states of gene activation (methylation) or repression (acetylation).
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-7546R-CY3

Anti-BCAM Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-7546R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7546R-CY3
Beschreibung: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12055R

Anti-5HT5A Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-12055R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12055R
Beschreibung: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.32234.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5063R-A680

Anti-GPAM Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5063R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5063R-A680
Beschreibung: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
UOM: 1 * 100 µl
Image Unavailable-733-2371

Zubehör für VWR® Imager CHEMI

Lieferant: Syngene (a division of the Synoptics group)
Beschreibung: Photodocumentation System, USB-Dongle für Netzwerklizenz

Image Unavailable-CAYM14955-50

HA-100 hydrochloride ≥95%

Lieferant: Cayman Chemical
Beschreibung: HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC<sub>50</sub>s = 8, 12 and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC<sub>50</sub> = 240 µM).

Product Image-786-254

Glycoprotein stain

Artikel-Nr: (786-254)
Lieferant: G-Biosciences
Hersteller Artikel Nummer : 786-254
Beschreibung: The stain uses an enhanced Periodic Acid-Schiff (PAS) method for detection of glycoprotein sugars. The supplied agent first oxidises the cis-diol sugar groups to aldehydes. The aldehyde groups react with the sensitive glycoprotein stain solution forming Schiff bonds and producing strong magenta colour bands. RAPIDstain™ can be used after glycoprotein staining to detect non-glycosylated proteins and the use of the stain enhances glycoprotein staining. The glycoprotein stainis highly convenient as all the key reagents required for staining are supplied and a unique positive & negative control is included.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-8259R

Anti-DHPS Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-8259R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8259R-CY5

Anti-DHPS Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-8259R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R-CY5
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5089R

Anti-C4ORF51 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-5089R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5089R
Beschreibung: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0013R-A555

Anti-CYCS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-0013R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-A555
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0013R-CY7

Anti-CYCS Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-0013R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-CY7
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl
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