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Lieferant: Cayman Chemical
Beschreibung: HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC<sub>50</sub>s = 8, 12 and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC<sub>50</sub> = 240 µM).

Artikel-Nr: (BOSSBS-6350R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6350R-A555
Beschreibung: Lysine methylation occurs in three distinct states, having either one (me1), two (me2) or three (me3) methyl groups attached to the amine group of the lysine side chain. In eukaryotes, histone H3 trimethylated at lysine 4 (H3K4me3) is associated with active chromatin and gene expression.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8259R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8259R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8259R-CY5
Beschreibung: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5089R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5089R
Beschreibung: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
UOM: 1 * 100 µl


Artikel-Nr: (ROCKMB-101-0500)
Lieferant: Rockland Immunochemicals
Hersteller Artikel Nummer : MB-101-0500
Beschreibung: Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin.
UOM: 1 * 0,5 KU


Artikel-Nr: (BOSSBS-0013R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-A350
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0013R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-CY5.5
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0013R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-A647
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7974R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7974R-CY3
Beschreibung: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-7974R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7974R-CY5.5
Beschreibung: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6142R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6142R
Beschreibung: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
UOM: 1 * 100 µl


Lieferant: Biotium
Beschreibung: CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 40,000 MW, and contains a formaldehyde-fixable free-amine group.

Lieferant: Apollo Scientific
Beschreibung: In base, hydroxyl groups react at the 4-position to yield heptafluoro-p-tolyl ethers, which can be used to protect estradiols.

Artikel-Nr: (40072.)
Lieferant: Biotium
Hersteller Artikel Nummer : 40072
Beschreibung: The amine reactive succinimidyl ester of EB (ethidium bromide) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in red fluorescence.
UOM: 1 * 5 mg


Lieferant: Biotium
Beschreibung: CF® Dyes with an azide group. Can be used to label or detect alkyne, BCN or cyclooctyne-containing molecules by fluorescence spectroscopy, microscopy or flow cytometry following copper-catalyzed azide-alkyne cycloaddition.

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