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Beschreibung: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Artikel-Nr: BOSSBS-10423R-A680
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-10423R-A680
Lieferant: Bioss


Beschreibung: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Artikel-Nr: BOSSBS-10423R-HRP
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-10423R-HRP
Lieferant: Bioss


Beschreibung: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Artikel-Nr: BOSSBS-5089R
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-5089R
Lieferant: Bioss


Beschreibung: CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 250,000 MW, and contains a formaldehyde-fixable free-amine group.
Artikel-Nr: 80134.
UOM: 1 * 1 mg
Hersteller Artikel Nummer : 80134
Lieferant: Biotium


Beschreibung: CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 10000 MW, and contains a formaldehyde-fixable free-amine group.
Artikel-Nr: 80110.
UOM: 1 * 1 mg
Hersteller Artikel Nummer : 80110
Lieferant: Biotium


Beschreibung: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
Artikel-Nr: BOSSBS-13140R-A488
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-13140R-A488
Lieferant: Bioss


Beschreibung: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
Artikel-Nr: BOSSBS-13140R-A647
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-13140R-A647
Lieferant: Bioss


Beschreibung: Electron carrier protein. The oxidised form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Artikel-Nr: BOSSBS-0013R-A680
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-0013R-A680
Lieferant: Bioss


Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Artikel-Nr: BOSSBS-0013R-HRP
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-0013R-HRP
Lieferant: Bioss


Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Artikel-Nr: BOSSBS-0013R-FITC
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-0013R-FITC
Lieferant: Bioss


Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Artikel-Nr: BOSSBS-0013R-A488
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-0013R-A488
Lieferant: Bioss


Beschreibung: The amine reactive succinimidyl ester of EB (ethidium bromide) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in red fluorescence.
Artikel-Nr: 40072.
UOM: 1 * 5 mg
Hersteller Artikel Nummer : 40072
Lieferant: Biotium


Beschreibung: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
Artikel-Nr: BOSSBS-12032R-A680
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-12032R-A680
Lieferant: Bioss


Beschreibung: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
Artikel-Nr: BOSSBS-5063R-A647
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-5063R-A647
Lieferant: Bioss


Beschreibung: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
Artikel-Nr: BOSSBS-5063R-A350
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-5063R-A350
Lieferant: Bioss


Beschreibung: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)
Artikel-Nr: BOSSBS-6249R-CY5
UOM: 1 * 100 µl
Hersteller Artikel Nummer : BS-6249R-CY5
Lieferant: Bioss